Lexus RX 450h vs. Lexus RX 350
iSeeCars' unbiased and data-driven comparison of the Lexus RX 450h and Lexus RX 350 contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the Lexus RX 450h and the Lexus RX 350.
When we compare the Lexus RX 450h's and the Lexus RX 350's specifications and ratings, the Lexus RX 450h has the advantage in the areas of fuel efficiency, reliability and base engine power. The Lexus RX 350 has the advantage in the areas of typical lower range of pricing for one- to five-year-old used cars, resale value, interior volume and overall quality score. Based on this comparison of the Lexus RX 450h's and the Lexus RX 350's specifications and ratings, the Lexus RX 350 is a better car than the Lexus RX 450h.
Pricing: A used 2022 Lexus RX 450h ranges from $39,998 to $54,414 while a used 2022 Lexus RX 350 is priced between $35,998 to $48,990.
Resale/Retained Value: Looking at the 5-year depreciation rate for both models, the Lexus RX 450h loses 40.6 percent of its value and the Lexus RX 350 loses 38.9 percent of its value. This means the Lexus RX 350 retains 1.7 percentage points more of its value and has the advantage of higher resale value versus the Lexus RX 450h.
Quality Rating: The iSeeCars Overall Quality rating for the Lexus RX 450h is 8.1 out of 10 while the Lexus RX 350's quality rating is 8.4 out of 10. This results in the Lexus RX 450h being ranked 3 out of 32 Best Luxury Hybrid SUVs and the Lexus RX 350 being ranked 3 out of 68 Best Luxury Crossover SUVs.
Reliability Rating: iSeeCars’ Reliability Rating for the Lexus RX 450h is 8.6 out of 10. For the Lexus RX 350 the reliability rating is 8.4 out of 10. This gives the Lexus RX 450h a slight advantage in reliability compared to the Lexus RX 350.
Engine Power and Fuel Efficiency Comparison: For engine performance, the Lexus RX 450h’s base engine makes 308 horsepower, and the Lexus RX 350 base engine makes 295 horsepower. The RX 450h is rated to deliver an average of 30 miles per gallon, with a highway range of 482 miles. The RX 350 is rated to deliver an average of 23 miles per gallon, with a highway range of 518 miles.This gives the Lexus RX 450h the advantage in fuel efficiency and the Lexus RX 350 the advantage in maximum range. The RX 450h uses premium unleaded, and the RX 350 uses regular unleaded.
Passenger Space Comparison: The Lexus RX 350, a crossover/midsize SUV, has the advantage of offering more interior volume, reflected in more and rear head room. The Lexus RX 450h and Lexus RX 350 are comparable in regards to front head room, front shoulder room, front leg room, rear shoulder room, rear leg room, and cargo space.
Safety Ratings: When comparing crash test ratings from NHTSA, the Lexus RX 450h has higher safety ratings than the Lexus RX 350, with an average rating of 4.45 out of 5 Stars compared to 4.38 out of 5 Stars.
New Car Pricing
Asking Price:
-
Starting MSRP:
48720
Category Avg Starting MSRP:
(Luxury Hybrid Midsize SUVs)
61958
Category Starting MSRP Range:
(Luxury Hybrid Midsize SUVs)
48720 - 83300
New Car Pricing
Asking Price:
-
Starting MSRP:
45920
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
67488
Category Starting MSRP Range:
(Luxury Midsize SUVs)
44090 - 119900
Used Car Pricing
Avg Used Car Price:
47423
Price Range:
39998 - 54414
Category Avg Price:
(Luxury Hybrid Midsize SUVs)
56642
Category Avg Price Range:
(Luxury Hybrid Midsize SUVs)
47423 - 82654
# Used Cars for Sale Nationally:
132
Avg Mileage of Used Cars for Sale:
41843
# Good or Great Deals:
35
Used Car Pricing
Avg Used Car Price:
42713
Price Range:
35998 - 48990
Category Avg Price:
(Luxury Midsize SUVs)
52935
Category Avg Price Range:
(Luxury Midsize SUVs)
35812 - 90529
# Used Cars for Sale Nationally:
755
Avg Mileage of Used Cars for Sale:
39670
# Good or Great Deals:
278
Lexus RX 450h Scores & Rankings
Overall Score:
8.1 / 10
Reliability:
8.6 / 10
Retained Value:
8.4 / 10
Safety:
7.4 / 10
Lexus RX 350 Scores & Rankings
Overall Score:
8.4 / 10
Reliability:
8.4 / 10
Retained Value:
8.5 / 10
Safety:
8.4 / 10
iSeeCars Reliability Insights for Lexus RX 450h
Remaining Life Expectancy (years):
15.1
Typical Category Remaining Life Expectancy:
(Luxury Hybrid Midsize SUVs)
15.1
Category Remaining Life Expectancy Range:
(Luxury Hybrid Midsize SUVs)
15.1 - 15.1
Chance of Reaching 200k Miles for a New Car:
0.44
iSeeCars Reliability Insights for Lexus RX 350
Remaining Life Expectancy (years):
13.8
Typical Category Remaining Life Expectancy:
(Luxury Midsize SUVs)
10.1
Category Remaining Life Expectancy Range:
(Luxury Midsize SUVs)
6.7 - 13.8
Chance of Reaching 200k Miles for a New Car:
0.335
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.0995134697947773
Typical Category Recalls:
(Luxury Hybrid Midsize SUVs)
3.4
Category Range for Recalls:
(Luxury Hybrid Midsize SUVs)
1.1 - 7.3
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.0279250608733872
Typical Category Recalls:
(Luxury Midsize SUVs)
3.1
Category Range for Recalls:
(Luxury Midsize SUVs)
1.0 - 13.7
Lexus RX 450h Rankings
Ranking
1 out of / 32Ranking
1 out of / 29Ranking
1 out of / 12Ranking
1 out of / 12Ranking
3 out of / 32Ranking
3 out of / 32Ranking
3 out of / 29Ranking
3 out of / 12Ranking
4 out of / 32Ranking
4 out of / 29Ranking
4 out of / 12Ranking
6 out of / 12Ranking
7 out of / 29Ranking
7 out of / 12Ranking
8 out of / 32Ranking
8 out of / 12Ranking
8 out of / 12Ranking
12 out of / 32Ranking
12 out of / 29Ranking
12 out of / 29Ranking
12 out of / 12Ranking
15 out of / 32Ranking
16 out of / 29Ranking
16 out of / 29Ranking
19 out of / 32Ranking
19 out of / 32Ranking
27 out of / 29Ranking
30 out of / 32Lexus RX 350 Rankings
Ranking
1 out of / 68Ranking
1 out of / 27Ranking
1 out of / 27Ranking
1 out of / 25Ranking
1 out of / 25Ranking
1 out of / 1Ranking
3 out of / 68Ranking
3 out of / 27Ranking
4 out of / 68Ranking
5 out of / 5Ranking
12 out of / 27Ranking
15 out of / 27Ranking
16 out of / 27Ranking
19 out of / 27Ranking
21 out of / 27Ranking
24 out of / 64Ranking
24 out of / 27Ranking
27 out of / 27Ranking
28 out of / 68Ranking
34 out of / 68Ranking
34 out of / 68Ranking
36 out of / 68Ranking
41 out of / 68Ranking
41 out of / 68Ranking
65 out of / 68Available Body Styles
SUV
Available Body Styles
SUV
Available Drivetrain Options
Hybrid
Available Drivetrain Options
Gasoline
Lexus RX 450h Trim Levels
Base, F SPORT, F SPORT Handling
Lexus RX 350 Trim Levels
Base, F SPORT, F SPORT Handling
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Safety Ratings
NHTSA Safety Rating (last 5 year average):
4.45 out of 5 Stars
2025 NHTSA Overall Rating:
4 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
4.38 out of 5 Stars
2025 NHTSA Overall Rating:
4 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Base Drivetrain Specs
Horsepower:
308 hp @ 6000 rpm
Torque:
Not yet available
Power-to-Weight Ratio (higher is better):
0.065 hp per pound
Towing capacity:
Not yet available
Base Drivetrain Specs
Horsepower:
295 hp @ 6300 rpm
Torque:
267 foot-lbs @ 4700 rpm
Power-to-Weight Ratio (higher is better):
0.070 hp per pound
Towing capacity:
Not yet available
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Continuously Variable Transmission (CVT Automatic)
Standard/Optional Drivetrain Type:
AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
31 / 28 / 30
Range (city/hwy):
533 / 482 miles
Recommended Fuel Type:
Premium Unleaded
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
20 / 27 / 23
Range (city/hwy):
384 / 518 miles
Recommended Fuel Type:
Regular Unleaded
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Standard
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Cooled/Ventilated Seats:
Available
Heated Seats
Available
Heated Steering Wheel:
Available
Parking Sensors:
Available
Roof Rack:
Available
Sunroof/Moonroof:
Available
Wireless Smartphone Charging:
Available
Air Suspension:
N/A
Automatic Parking:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Trailer Hitch:
N/A
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Standard
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Cooled/Ventilated Seats:
Available
Heated Seats
Available
Heated Steering Wheel:
Available
Parking Sensors:
Available
Roof Rack:
Available
Sunroof/Moonroof:
Available
Wireless Smartphone Charging:
Available
Air Suspension:
N/A
Automatic Parking:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Trailer Hitch:
N/A
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Rear Seat Reminder:
N/A
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Rear Seat Reminder:
N/A
Interior Dimensions
Front Head Room:
39.4 inches
Front Leg Room:
44.1 inches
Front Shoulder Room:
57.8 inches
Rear Head Room:
38.2 inches
Rear Leg Room:
38 inches
Rear Shoulder Room:
57.6 inches
Cargo Space:
16 cubic feet
Cargo Space, 2nd-row seat folded down:
32.6 cubic feet
Overall Interior Volume:
114.1 cubic feet
Interior Dimensions
Front Head Room:
39.4 inches
Front Leg Room:
44.1 inches
Front Shoulder Room:
57.8 inches
Rear Head Room:
39.1 inches
Rear Leg Room:
38 inches
Rear Shoulder Room:
57.6 inches
Cargo Space:
16 cubic feet
Cargo Space, 2nd-row seat folded down:
32.6 cubic feet
Overall Interior Volume:
115.8 cubic feet
Exterior Dimensions
Curb Weight:
4740 lbs
Width:
74.6 inches
Height:
67.7 inches
Length:
192.5 inches
Wheelbase:
109.8 inches
Ground Clearance:
8.2 inches
Exterior Dimensions
Curb Weight:
4222 lbs
Width:
74.6 inches
Height:
67.7 inches
Length:
192.5 inches
Wheelbase:
109.8 inches
Ground Clearance:
8.2 inches
Standard Wheel/Tire Information
Wheel Size:
18.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/65R18
Standard Wheel/Tire Information
Wheel Size:
18.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/65R18
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Nebula Gray Pearl
Green
Nori Green Pearl
Red
Matador Red Mica
Silver
Atomic Silver
White
Eminent White Pearl
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Nebula Gray Pearl
Green
Nori Green Pearl
Red
Matador Red Mica
Silver
Atomic Silver
White
Eminent White Pearl
Interior Colors
Beige
Parchment w/Gray Sapele Wood and Aluminum Trim / Parchment w/Matte Bamboo Trim / Parchment w/Striated Black Trim
Black
Black w/Gray Sapele Wood and Aluminum Trim / Black w/Matte Walnut Trim / Black w/Open Pore Black Walnut Trim and White Accents and Gray Stitching / Black w/Striated Black Trim
Brown
Glazed Caramel w/Gray Sapele Wood and Aluminum Trim / Glazed Caramel w/Matte Walnut Trim
Gray
Birch w/Gray Sapele Wood and Aluminum Trim / Birch w/Matte Walnut Trim / Birch w/Striated Black Trim
Interior Colors
Beige
Parchment w/Gray Sapele Wood and Aluminum Trim / Parchment w/Matte Bamboo Trim / Parchment w/Striated Black Trim
Black
Black w/Gray Sapele Wood and Aluminum Trim / Black w/Matte Walnut Trim / Black w/Open Pore Black Walnut Trim and White Accents and Gray Stitching / Black w/Striated Black Trim
Brown
Glazed Caramel w/Gray Sapele Wood and Aluminum Trim / Glazed Caramel w/Matte Walnut Trim
Gray
Birch w/Gray Sapele Wood and Aluminum Trim / Birch w/Matte Walnut Trim / Birch w/Striated Black Trim
