Lexus RX 350L vs. Acura MDX
iSeeCars' unbiased and data-driven comparison of the Lexus RX 350L and Acura MDX contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the Lexus RX 350L and the Acura MDX.
When comparing the Lexus RX 350L's and the Acura MDX's specifications and ratings, the Lexus RX 350L has the advantage in the areas of reliability and resale value. The Acura MDX has the advantage in the areas of typical lower range of pricing for one- to five-year-old used cars, interior volume and overall quality score. The Lexus RX 350L and Acura MDX have the same fuel efficiency base engine power. Based on this comparison of the Lexus RX 350L's and the Acura MDX's specifications and ratings, the Acura MDX is a better car than the Lexus RX 350L.
Pricing: A used 2022 Lexus RX 350L ranges from $37,079 to $48,942 while a used 2022 Acura MDX is priced between $33,129 to $49,897.
Resale/Retained Value: Looking at the 5-year depreciation rate for both models, the Lexus RX 350L loses 42 percent of its value and the Acura MDX loses 53.7 percent of its value. This means the Lexus RX 350L retains 11.7 percentage points more of its value and has the advantage of higher resale value versus the Acura MDX.
Quality Rating: The iSeeCars Overall Quality rating for the Lexus RX 350L is 7.9 out of 10 while the Acura MDX's quality rating is 8.5 out of 10. This results in the Lexus RX 350L being ranked 7 out of 27 Best Luxury Midsize SUVs and the Acura MDX being ranked 3 out of 27. Out of 29 Best Luxury SUVs with 3 Rows, the Lexus RX 350L is ranked 8 and the Acura MDX is ranked 4. The Lexus RX 350L is also ranked 10 out of 68 Best Luxury Crossover SUVs while the Acura MDX is ranked 6 out of 68.
Reliability Rating: iSeeCars’ Reliability Rating for the Lexus RX 350L is 8.4 out of 10. For the Acura MDX the reliability rating is 8.0 out of 10. This gives the Lexus RX 350L a slight advantage in reliability compared to the Acura MDX.
Engine Power and Fuel Efficiency Comparison: For engine performance, the base engine of both the Lexus RX 350L and the Acura MDX makes 290 horsepower. The RX 350L is rated to deliver an average of 22 miles per gallon, with a highway range of 499 miles. The MDX is rated to deliver an average of 22 miles per gallon, with a highway range of 481 miles.This gives the Acura MDX the advantage in fuel efficiency and the Lexus RX 350L the advantage in maximum range. The RX 350L uses regular unleaded, and the MDX uses premium unleaded.
Passenger Space Comparison: While both models are crossover/midsize SUVs, the Acura MDX has the advantage of offering more interior volume, reflected in more front shoulder room, front leg room, rear shoulder room, rear leg room, and cargo space. The Lexus RX 350L has the advantage in the areas of front head room and rear head room.
Safety Ratings: When comparing crash test ratings from NHTSA, the Acura MDX has higher safety ratings than the Lexus RX 350L, with an average rating of 5 out of 5 Stars compared to 4 out of 5 Stars.
New Car Pricing
Asking Price:
-
Starting MSRP:
48750
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
67488
Category Starting MSRP Range:
(Luxury Midsize SUVs)
44090 - 119900
New Car Pricing
Asking Price:
-
Starting MSRP:
48000
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
67488
Category Starting MSRP Range:
(Luxury Midsize SUVs)
44090 - 119900
Used Car Pricing
Avg Used Car Price:
42889
Price Range:
37079 - 48942
Category Avg Price:
(Luxury Midsize SUVs)
52935
Category Avg Price Range:
(Luxury Midsize SUVs)
35812 - 90529
# Used Cars for Sale Nationally:
93
Avg Mileage of Used Cars for Sale:
55365
# Good or Great Deals:
7
Used Car Pricing
Avg Used Car Price:
40643
Price Range:
33129 - 49897
Category Avg Price:
(Luxury Midsize SUVs)
52935
Category Avg Price Range:
(Luxury Midsize SUVs)
35812 - 90529
# Used Cars for Sale Nationally:
511
Avg Mileage of Used Cars for Sale:
62953
# Good or Great Deals:
50
Lexus RX 350L Scores & Rankings
Overall Score:
7.9 / 10
Reliability:
8.4 / 10
Retained Value:
8.3 / 10
Safety:
7.0 / 10
Acura MDX Scores & Rankings
Overall Score:
8.5 / 10
Reliability:
8.0 / 10
Retained Value:
7.6 / 10
Safety:
10.0 / 10
iSeeCars Reliability Insights for Lexus RX 350L
Remaining Life Expectancy (years):
13.8
Typical Category Remaining Life Expectancy:
(Luxury Midsize SUVs)
10.1
Category Remaining Life Expectancy Range:
(Luxury Midsize SUVs)
6.7 - 13.8
Chance of Reaching 200k Miles for a New Car:
0.335
iSeeCars Reliability Insights for Acura MDX
Remaining Life Expectancy (years):
10.1
Typical Category Remaining Life Expectancy:
(Luxury Midsize SUVs)
10.1
Category Remaining Life Expectancy Range:
(Luxury Midsize SUVs)
6.7 - 13.8
Chance of Reaching 200k Miles for a New Car:
0.317
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.0346178394295942
Typical Category Recalls:
(Luxury Midsize SUVs)
3.1
Category Range for Recalls:
(Luxury Midsize SUVs)
1.0 - 13.7
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
4.984290466015009
Typical Category Recalls:
(Luxury Midsize SUVs)
3.1
Category Range for Recalls:
(Luxury Midsize SUVs)
1.0 - 13.7
Lexus RX 350L Rankings
Ranking
3 out of / 68Ranking
4 out of / 29Ranking
4 out of / 27Ranking
5 out of / 29Ranking
5 out of / 27Ranking
7 out of / 27Ranking
8 out of / 68Ranking
8 out of / 29Ranking
9 out of / 27Ranking
10 out of / 68Ranking
13 out of / 27Ranking
13 out of / 27Ranking
19 out of / 29Ranking
20 out of / 68Ranking
20 out of / 29Ranking
20 out of / 29Ranking
20 out of / 29Ranking
21 out of / 27Ranking
22 out of / 27Ranking
23 out of / 27Ranking
25 out of / 27Ranking
25 out of / 27Ranking
27 out of / 29Ranking
28 out of / 68Ranking
28 out of / 29Ranking
28 out of / 29Ranking
29 out of / 29Ranking
34 out of / 68Ranking
35 out of / 68Ranking
37 out of / 68Ranking
40 out of / 68Ranking
43 out of / 68Ranking
63 out of / 68Acura MDX Rankings
Ranking
1 out of / 7Ranking
1 out of / 6Ranking
2 out of / 13Ranking
2 out of / 6Ranking
3 out of / 29Ranking
3 out of / 27Ranking
3 out of / 27Ranking
3 out of / 23Ranking
3 out of / 23Ranking
3 out of / 13Ranking
3 out of / 7Ranking
4 out of / 29Ranking
5 out of / 29Ranking
5 out of / 27Ranking
5 out of / 26Ranking
6 out of / 68Ranking
6 out of / 29Ranking
6 out of / 27Ranking
7 out of / 68Ranking
8 out of / 29Ranking
9 out of / 68Ranking
9 out of / 29Ranking
9 out of / 27Ranking
9 out of / 27Ranking
10 out of / 27Ranking
12 out of / 27Ranking
13 out of / 68Ranking
13 out of / 68Ranking
14 out of / 27Ranking
17 out of / 29Ranking
17 out of / 27Ranking
18 out of / 29Ranking
19 out of / 68Ranking
19 out of / 27Ranking
19 out of / 27Ranking
21 out of / 29Ranking
22 out of / 29Ranking
22 out of / 29Ranking
23 out of / 68Ranking
23 out of / 29Ranking
23 out of / 27Ranking
24 out of / 29Ranking
27 out of / 68Ranking
32 out of / 60Ranking
33 out of / 68Ranking
36 out of / 68Ranking
41 out of / 68Ranking
49 out of / 68Ranking
51 out of / 68Available Body Styles
SUV
Available Body Styles
SUV
Available Drivetrain Options
Gasoline
Available Drivetrain Options
Gasoline
Lexus RX 350L Trim Levels
Base, Luxury
Acura MDX Trim Levels
Base, SH-AWD, SH-AWD Type S, SH-AWD Type S w/Advance Package, SH-AWD w/A-SPEC, SH-AWD w/Advance, SH-AWD w/Tech, w/Tech
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years / 50000 miles
Safety Ratings
NHTSA Safety Rating (last 5 year average):
4 out of 5 Stars
2026 NHTSA Overall Rating:
4 out of 5 Stars
2026 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2026 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2026 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2026 NHTSA Overall Rating:
4 out of 5 Stars
2026 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2026 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2026 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Base Drivetrain Specs
Horsepower:
290 hp @ 6300 rpm
Torque:
263 foot-lbs @ 4700 rpm
Power-to-Weight Ratio (higher is better):
0.065 hp per pound
Towing capacity:
Not yet available
Base Drivetrain Specs
Horsepower:
290 hp @ 6200 rpm
Torque:
267 foot-lbs @ 4700 rpm
Power-to-Weight Ratio (higher is better):
0.068 hp per pound
Towing capacity:
Not yet available
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
19 / 26 / 22
Range (city/hwy):
365 / 499 miles
Recommended Fuel Type:
Regular Unleaded
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
19 / 26 / 22
Range (city/hwy):
352 / 481 miles
Recommended Fuel Type:
Premium Unleaded
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Standard
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Captain's seat:
Available
Cooled/Ventilated Seats:
Available
Heated Seats
Available
Heated Steering Wheel:
Available
Parking Sensors:
Available
Quad Seats:
Available
Roof Rack:
Available
Sunroof/Moonroof:
Available
Wireless Smartphone Charging:
Available
Air Suspension:
N/A
Automatic Parking:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Trailer Hitch:
N/A
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Internet Radio:
N/A
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Available
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Captain's seat:
N/A
Cooled/Ventilated Seats:
Available
Heated Seats
Standard
Heated Steering Wheel:
Available
Parking Sensors:
Available
Quad Seats:
N/A
Roof Rack:
Available
Sunroof/Moonroof:
Standard
Wireless Smartphone Charging:
Standard
Air Suspension:
Available
Automatic Parking:
N/A
Front Bench Seats:
N/A
Massage Seats:
Available
Panoramic Sunroof/Moonroof
N/A
Trailer Hitch:
Available
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Rear Seat Reminder:
N/A
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
360-Degree Camera:
Available
Driver Attention Monitoring:
Standard
Rear Seat Reminder:
Standard
Interior Dimensions
Front Head Room:
39.8 inches
Front Leg Room:
41.4 inches
Front Shoulder Room:
58.3 inches
Rear Head Room:
38.5 inches
Rear Leg Room:
30.9 inches
Rear Shoulder Room:
57.8 inches
Cargo Space:
7.5 cubic feet
Cargo Space, 2nd-row seat folded down:
58.5 cubic feet
Overall Interior Volume:
124.5 cubic feet
Interior Dimensions
Front Head Room:
38.5 inches
Front Leg Room:
41.6 inches
Front Shoulder Room:
61.9 inches
Rear Head Room:
38.1 inches
Rear Leg Room:
38.5 inches
Rear Shoulder Room:
60.3 inches
Cargo Space:
16.3 cubic feet
Cargo Space, 2nd-row seat folded down:
71.4 cubic feet
Overall Interior Volume:
155.4 cubic feet
Exterior Dimensions
Curb Weight:
4464 lbs
Width:
74.6 inches
Height:
67.3 inches
Length:
196.9 inches
Wheelbase:
109.8 inches
Ground Clearance:
8.1 inches
Exterior Dimensions
Curb Weight:
4271 lbs
Width:
78.7 inches
Height:
67.1 inches
Length:
198.4 inches
Wheelbase:
113.8 inches
Ground Clearance:
7.3 inches
Standard Wheel/Tire Information
Wheel Size:
18.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/65R18
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.5 inches
Wheel Type:
aluminum alloy
Tire Size:
255/55R19
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Cloudburst Gray
Green
Nori Green Pearl
Red
Matador Red Mica
Silver
Iridium
White
Eminent White Pearl
Exterior Colors
Black
Majestic Black Pearl
Blue
Fathom Blue Pearl
Gray
Liquid Carbon Metallic
Green
Not available
Red
Performance Red Pearl
Silver
Lunar Silver Metallic
White
Platinum White Pearl
Interior Colors
Beige
Parchment w/Matte Bamboo Trim / Parchment w/Striated Black Trim
Black
Black w/Open Pore Black Walnut Trim and Blue Stitching / Black w/Open-Pore Brown Walnut Trim / Black w/Striated Black Trim
Brown
Glazed Carmel w/Open-Pore Brown Walnut Trim
Gray
Birch w/Open-Pore Brown Walnut Trim / Birch w/Striated Black Trim
Interior Colors
Beige
Parchment
Black
Ebony
Brown
Not available
Gray
Not available
