Lexus IS 350 vs. Lexus RX 350
iSeeCars' unbiased and data-driven comparison of the Lexus IS 350 and Lexus RX 350 contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the Lexus IS 350 and the Lexus RX 350.
In comparing the Lexus IS 350's and the Lexus RX 350's specifications and ratings, the Lexus IS 350 has the advantage in the areas of new vehicle base pricing, typical lower range of pricing for one- to five-year-old used cars, reliability, resale value, overall quality score and base engine power. The Lexus RX 350 has the advantage in the area of fuel efficiency. Based on this comparison of the Lexus IS 350's and the Lexus RX 350's specifications and ratings, the Lexus IS 350 is a better car than the Lexus RX 350.
Pricing: A used 2024 Lexus IS 350 ranges from $41,646 to $54,683 while a used 2024 Lexus RX 350 is priced between $52,993 to $66,936. For a new model, the Lexus IS 350's price is between $45,913 and $58,327, with the Lexus RX 350 priced between $52,880 and $67,145.
Resale/Retained Value: Looking at the 5-year depreciation rate for both models, the Lexus IS 350 loses 37.3 percent of its value and the Lexus RX 350 loses 42.5 percent of its value. This means the Lexus IS 350 retains 5.2 percentage points more of its value and has the advantage of higher resale value versus the Lexus RX 350.
Quality Rating: The iSeeCars Overall Quality rating for the Lexus IS 350 is 9.1 out of 10 while the Lexus RX 350's quality rating is 8.4 out of 10. This results in the Lexus IS 350 being ranked 1 out of 36 Best Luxury Small Cars and the Lexus RX 350 being ranked 2 out of 20 Best Luxury Midsize SUVs.
Reliability Rating: iSeeCars’ Reliability Rating for the Lexus IS 350 is 9.0 out of 10. For the Lexus RX 350 the reliability rating is 8.9 out of 10. This gives the Lexus IS 350 a slight advantage in reliability compared to the Lexus RX 350.
Engine Power and Fuel Efficiency Comparison: For engine performance, the Lexus IS 350’s base engine makes 311 horsepower, and the Lexus RX 350 base engine makes 275 horsepower. The IS 350 is rated to deliver an average of 23 miles per gallon, with a highway range of 487 miles. The RX 350 is rated to deliver an average of 25 miles per gallon, with a highway range of 516 miles. This gives the Lexus RX 350 the fuel efficiency and maximum range advantage over the Lexus IS 350. Both models use premium unleaded.
Safety Ratings: When comparing crash test ratings from NHTSA, the Lexus IS 350 has higher safety ratings than the Lexus RX 350, with an average rating of 5 out of 5 Stars compared to 4.42 out of 5 Stars. When comparing IIHS evaluations, the Lexus RX 350 has the advantage with a Top Safety Pick award.
New Car Pricing
Asking Price:
$45,913 - $58,327
Starting MSRP:
$43,260
Category Avg Starting MSRP:
(Luxury Compact Cars)
$48,375
Category Starting MSRP Range:
(Luxury Compact Cars)
$31,800 - $79,900
New Car Pricing
Asking Price:
$52,880 - $67,145
Starting MSRP:
$48,600
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
$72,087
Category Starting MSRP Range:
(Luxury Midsize SUVs)
$48,600 - $127,200
Used Car Pricing
Avg Used Car Price:
$47,863
Price Range:
$41,646 - $54,683
Category Avg Price:
(Luxury Compact Cars)
$52,490
Category Avg Price Range:
(Luxury Compact Cars)
$35,163 - $100,522
# Used Cars for Sale Nationally:
145
Avg Mileage of Used Cars for Sale:
5,357
# Good or Great Deals:
24
Used Car Pricing
Avg Used Car Price:
$59,910
Price Range:
$52,993 - $66,936
Category Avg Price:
(Luxury Midsize SUVs)
$82,938
Category Avg Price Range:
(Luxury Midsize SUVs)
$54,923 - $133,203
# Used Cars for Sale Nationally:
578
Avg Mileage of Used Cars for Sale:
5,932
# Good or Great Deals:
62
5-year Depreciation
Depreciation $:
$16,492
Depreciation %:
38.1%
Resale Value $:
$26,768
Residual Value %:
61.9%
Typical Category Depreciation %:
(Luxury Compact Cars)
48.9%
Category Depreciation Range:
(Luxury Compact Cars)
33.5% - 53.5%
5-year Depreciation
Depreciation $:
$21,021
Depreciation %:
43.3%
Resale Value $:
$27,579
Residual Value %:
56.7%
Typical Category Depreciation %:
(Luxury Midsize SUVs)
53.4%
Category Depreciation Range:
(Luxury Midsize SUVs)
43.3% - 61%
Lexus IS 350 Scores & Rankings
Overall Score:
9.1 / 10
Reliability:
9.0 / 10
Retained Value:
8.2 / 10
Safety:
10.0 / 10
Lexus RX 350 Scores & Rankings
Overall Score:
8.4 / 10
Reliability:
8.9 / 10
Retained Value:
7.9 / 10
Safety:
8.4 / 10
iSeeCars Reliability Insights for Lexus IS 350
Avg Life Expectancy (years):
14.3
Typical Category Life Expectancy:
(Luxury Compact Cars)
10.6
Category Life Expectancy Range:
(Luxury Compact Cars)
8.1 - 14.3
Chance of Reaching 200k Miles for a New Car:
60.2%
iSeeCars Reliability Insights for Lexus RX 350
Avg Life Expectancy (years):
12.8
Typical Category Life Expectancy:
(Luxury Midsize SUVs)
10.1
Category Life Expectancy Range:
(Luxury Midsize SUVs)
7.9 - 12.8
Chance of Reaching 200k Miles for a New Car:
49.6%
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.6
Typical Category Recalls:
(Luxury Compact Cars)
2.2
Category Range for Recalls:
(Luxury Compact Cars)
1.2 - 14.6
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.5
Typical Category Recalls:
(Luxury Midsize SUVs)
3.8
Category Range for Recalls:
(Luxury Midsize SUVs)
0.8 - 41.1
Lexus IS 350 Rankings
Ranking
1 out of / 36Ranking
1 out of / 36Ranking
1 out of / 36Ranking
1 out of / 12Ranking
3 out of / 36Ranking
5 out of / 36Ranking
11 out of / 31Ranking
18 out of / 36Ranking
20 out of / 36Ranking
27 out of / 36Lexus RX 350 Rankings
Ranking
1 out of / 20Ranking
1 out of / 19Ranking
1 out of / 1Ranking
2 out of / 68Ranking
2 out of / 20Ranking
3 out of / 20Ranking
3 out of / 10Ranking
5 out of / 68Ranking
6 out of / 6Ranking
7 out of / 68Ranking
10 out of / 20Ranking
10 out of / 20Ranking
12 out of / 20Ranking
14 out of / 20Ranking
16 out of / 20Ranking
17 out of / 20Ranking
20 out of / 20Ranking
21 out of / 59Ranking
26 out of / 68Ranking
32 out of / 68Ranking
37 out of / 68Ranking
37 out of / 68Ranking
40 out of / 68Ranking
42 out of / 68Ranking
62 out of / 68Available Body Styles
Sedan
Available Body Styles
SUV
Available Drivetrain Options
Gasoline
Available Drivetrain Options
Gasoline
Lexus IS 350 Trim Levels
F SPORT, F SPORT Design
Lexus RX 350 Trim Levels
Base, F SPORT Handling, Luxury, Premium, Premium+
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2025 NHTSA Overall Rating:
5 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
5 out of 5 Stars
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
4.42 out of 5 Stars
2025 NHTSA Overall Rating:
4 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
TOP SAFETY PICK
Base Drivetrain Specs
Horsepower:
311 hp @ 6600 rpm
Torque:
280 foot-lbs @ 4800 rpm
Power-to-Weight Ratio (higher is better):
0.083 hp per pound
Towing capacity:
Not yet available
Base Drivetrain Specs
Horsepower:
275 hp @ 6000 rpm
Torque:
317 foot-lbs @ 1700 rpm
Power-to-Weight Ratio (higher is better):
0.066 hp per pound
Towing capacity:
Not yet available
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
RWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
20 / 28 / 23
Range (city/hwy):
348 / 487 miles
Recommended Fuel Type:
Premium Unleaded
Engine Specifications
Engine Size:
2.4 liters
Engine Configuration:
Inline
Number of Cylinders:
4
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
22 / 29 / 25
Range (city/hwy):
392 / 516 miles
Recommended Fuel Type:
Premium Unleaded
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Paddle Shifters:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Navigation System:
Available
Parking Sensors:
Available
Sunroof/Moonroof:
Available
Air Suspension:
N/A
Automatic Parking:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Power Lift Gate:
N/A
Quad Seats:
N/A
Roof Rack:
N/A
Trailer Hitch:
N/A
Wireless Smartphone Charging:
N/A
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Paddle Shifters:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Navigation System:
Standard
Parking Sensors:
Standard
Sunroof/Moonroof:
Available
Air Suspension:
N/A
Automatic Parking:
Available
Captain's seat:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Power Lift Gate:
Standard
Quad Seats:
N/A
Roof Rack:
Available
Trailer Hitch:
Available
Wireless Smartphone Charging:
Available
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Rear Seat Reminder:
N/A
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Rear Seat Reminder:
Standard
Interior Dimensions
Front Head Room:
38.2 inches
Front Leg Room:
44.8 inches
Front Shoulder Room:
55.9 inches
Rear Head Room:
36.9 inches
Rear Leg Room:
32.2 inches
Rear Shoulder Room:
53.4 inches
Cargo Space:
10.8 cubic feet
Cargo Space, 2nd-row seat folded down:
Not yet available
Overall Interior Volume:
90.2 cubic feet
Interior Dimensions
Front Head Room:
39.5 inches
Front Leg Room:
41.1 inches
Front Shoulder Room:
58.1 inches
Rear Head Room:
38.6 inches
Rear Leg Room:
37.4 inches
Rear Shoulder Room:
56.5 inches
Cargo Space:
29.6 cubic feet
Cargo Space, 2nd-row seat folded down:
46.2 cubic feet
Overall Interior Volume:
Not yet available
Exterior Dimensions
Curb Weight:
3748 lbs
Width:
72.4 inches
Height:
56.5 inches
Length:
185.4 inches
Wheelbase:
110.2 inches
Ground Clearance:
5.5 inches
Exterior Dimensions
Curb Weight:
4155 lbs
Width:
75.6 inches
Height:
67.3 inches
Length:
192.5 inches
Wheelbase:
112.2 inches
Ground Clearance:
8.2 inches
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.5 inches
Wheel Type:
painted aluminum alloy
Tire Size:
235/35R19
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/60R19
Exterior Colors
Black
Caviar
Blue
Ultrasonic Blue Mica 2.0
Gray
Cloudburst Gray / Incognito
Red
Infrared
Silver
Iridium
White
Ultra White
Green
Not available
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Cloudburst Gray
Red
Matador Red Mica
Silver
Iridium
White
Eminent White Pearl
Green
Nori Green Pearl
Interior Colors
Black
Black w/ Black Metallic Trim
Brown
Glazed Caramel w/ Black Metallic Trim
Red
Rioja Red w/ Black Metallic Trim
White
Not available
Interior Colors
Black
Black w/ Black Cascade Trim
Brown
Not available
Red
Not available
White
Macadamia w/ Black Cascade Trim