
2022 Acura MDX vs. 2022 Lexus RX 350L
iSeeCars' unbiased and data-driven comparison of the 2022 Acura MDX and 2022 Lexus RX 350L contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the 2022 Acura MDX and the 2022 Lexus RX 350L.
When comparing the 2022 Acura MDX's and the 2022 Lexus RX 350L's specifications and ratings, the 2022 Acura MDX has the advantage in the areas of typical lower range of pricing for used cars, interior volume and overall quality score. The 2022 Lexus RX 350L has the advantage in the areas of reliability and resale value. The 2022 Acura MDX and 2022 Lexus RX 350L have the same fuel efficiency base engine power. Based on this comparison of the 2022 Acura MDX's and the 2022 Lexus RX 350L's specifications and ratings, the 2022 Acura MDX is a better car than the 2022 Lexus RX 350L.
Pricing: A used 2022 Acura MDX ranges from $33,129 to $49,897 while a used 2022 Lexus RX 350L is priced between $37,079 to $48,942.
Resale/Retained Value: Looking at the 5-year depreciation rate for both models, the 2022 Acura MDX loses 53.7 percent of its value and the 2022 Lexus RX 350L loses 42 percent of its value. This means the 2022 Lexus RX 350L retains 11.7 percentage points more of its value and has the advantage of higher resale value versus the 2022 Acura MDX.
Quality Rating: The iSeeCars Overall Quality rating for the Acura MDX is 8.5 out of 10 while the Lexus RX 350L's quality rating is 7.9 out of 10. This results in the Acura MDX being ranked 3 out of 27 Best Luxury Midsize SUVs and the Lexus RX 350L being ranked 7 out of 27. Out of 29 Best Luxury SUVs with 3 Rows, the Acura MDX is ranked 4 and the Lexus RX 350L is ranked 8. The Acura MDX is also ranked 6 out of 68 Best Luxury Crossover SUVs while the Lexus RX 350L is ranked 10 out of 68.
Reliability Rating: iSeeCars’ Reliability Rating for the Acura MDX is 8.0 out of 10. For the Lexus RX 350L the reliability rating is 8.4 out of 10. This gives the Lexus RX 350L a slight advantage in reliability compared to the Acura MDX.
Engine Power and Fuel Efficiency Comparison: For engine performance, the base engine of both the 2022 Acura MDX and the 2022 Lexus RX 350L makes 290 horsepower. The MDX is rated to deliver an average of 22 miles per gallon, with a highway range of 481 miles. The RX 350L is rated to deliver an average of 22 miles per gallon, with a highway range of 499 miles. This gives the 2022 Lexus RX 350L the fuel efficiency and maximum range advantage over the 2022 Acura MDX. The MDX uses premium unleaded, and the RX 350L uses regular unleaded.
Passenger Space Comparison: While both models are crossover/midsize SUVs, the 2022 Acura MDX has the advantage of offering more interior volume, reflected in more front shoulder room, front leg room, rear shoulder room, rear leg room, and cargo space. The 2022 Lexus RX 350L has the advantage in the areas of front head room and rear head room.
Safety Ratings: When comparing crash test ratings from NHTSA, the 2022 Acura MDX has higher safety ratings than the 2022 Lexus RX 350L, with an average rating of 5 out of 5 Stars compared to 4 out of 5 Stars.
New Car Pricing
Asking Price:
-
Starting MSRP:
48000
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
67488
Category Starting MSRP Range:
(Luxury Midsize SUVs)
44090 - 119900
New Car Pricing
Asking Price:
-
Starting MSRP:
48750
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
67488
Category Starting MSRP Range:
(Luxury Midsize SUVs)
44090 - 119900
Used Car Pricing
Avg Used Car Price:
40643
Price Range:
33129 - 49897
Category Avg Price:
(Luxury Midsize SUVs)
52935
Category Avg Price Range:
(Luxury Midsize SUVs)
35812 - 90529
# Used Cars for Sale Nationally:
511
Avg Mileage of Used Cars for Sale:
62953
# Good or Great Deals:
50
Used Car Pricing
Avg Used Car Price:
42889
Price Range:
37079 - 48942
Category Avg Price:
(Luxury Midsize SUVs)
52935
Category Avg Price Range:
(Luxury Midsize SUVs)
35812 - 90529
# Used Cars for Sale Nationally:
93
Avg Mileage of Used Cars for Sale:
55365
# Good or Great Deals:
7
Acura MDX Scores & Rankings
Overall Score:
8.5 / 10
Reliability:
8.0 / 10
Retained Value:
7.6 / 10
Safety:
10.0 / 10
Lexus RX 350L Scores & Rankings
Overall Score:
7.9 / 10
Reliability:
8.4 / 10
Retained Value:
8.3 / 10
Safety:
7.0 / 10
iSeeCars Reliability Insights for 2022 Acura MDX
Remaining Life Expectancy (years):
10.1
Typical Category Remaining Life Expectancy:
(Luxury Midsize SUVs)
10.1
Category Remaining Life Expectancy Range:
(Luxury Midsize SUVs)
6.7 - 13.8
Chance of Reaching 200k Miles for a New Car:
0.317
iSeeCars Reliability Insights for 2022 Lexus RX 350L
Remaining Life Expectancy (years):
13.8
Typical Category Remaining Life Expectancy:
(Luxury Midsize SUVs)
10.1
Category Remaining Life Expectancy Range:
(Luxury Midsize SUVs)
6.7 - 13.8
Chance of Reaching 200k Miles for a New Car:
0.335
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
4.984290466015009
Typical Category Recalls:
(Luxury Midsize SUVs)
3.1
Category Range for Recalls:
(Luxury Midsize SUVs)
1.0 - 13.7
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.0346178394295942
Typical Category Recalls:
(Luxury Midsize SUVs)
3.1
Category Range for Recalls:
(Luxury Midsize SUVs)
1.0 - 13.7
Acura MDX Rankings
Ranking
1 out of / 7Ranking
1 out of / 6Ranking
2 out of / 13Ranking
2 out of / 6Ranking
3 out of / 29Ranking
3 out of / 27Ranking
3 out of / 27Ranking
3 out of / 23Ranking
3 out of / 23Ranking
3 out of / 13Ranking
3 out of / 7Ranking
4 out of / 29Ranking
5 out of / 29Ranking
5 out of / 27Ranking
5 out of / 26Ranking
6 out of / 68Ranking
6 out of / 29Ranking
6 out of / 27Ranking
7 out of / 68Ranking
8 out of / 29Ranking
9 out of / 68Ranking
9 out of / 29Ranking
9 out of / 27Ranking
9 out of / 27Ranking
10 out of / 27Ranking
12 out of / 27Ranking
13 out of / 68Ranking
13 out of / 68Ranking
14 out of / 27Ranking
17 out of / 29Ranking
17 out of / 27Ranking
18 out of / 29Ranking
19 out of / 68Ranking
19 out of / 27Ranking
19 out of / 27Ranking
21 out of / 29Ranking
22 out of / 29Ranking
22 out of / 29Ranking
23 out of / 68Ranking
23 out of / 29Ranking
23 out of / 27Ranking
24 out of / 29Ranking
27 out of / 68Ranking
32 out of / 60Ranking
33 out of / 68Ranking
36 out of / 68Ranking
41 out of / 68Ranking
49 out of / 68Ranking
51 out of / 68Lexus RX 350L Rankings
Ranking
3 out of / 68Ranking
4 out of / 29Ranking
4 out of / 27Ranking
5 out of / 29Ranking
5 out of / 27Ranking
7 out of / 27Ranking
8 out of / 68Ranking
8 out of / 29Ranking
9 out of / 27Ranking
10 out of / 68Ranking
13 out of / 27Ranking
13 out of / 27Ranking
19 out of / 29Ranking
20 out of / 68Ranking
20 out of / 29Ranking
20 out of / 29Ranking
20 out of / 29Ranking
21 out of / 27Ranking
22 out of / 27Ranking
23 out of / 27Ranking
25 out of / 27Ranking
25 out of / 27Ranking
27 out of / 29Ranking
28 out of / 68Ranking
28 out of / 29Ranking
28 out of / 29Ranking
29 out of / 29Ranking
34 out of / 68Ranking
35 out of / 68Ranking
37 out of / 68Ranking
40 out of / 68Ranking
43 out of / 68Ranking
63 out of / 68Available Body Styles
SUV
Available Body Styles
SUV
Available Drivetrain Options
Gasoline
Available Drivetrain Options
Gasoline
2022 Acura MDX Trim Levels
Base, SH-AWD, SH-AWD Type S, SH-AWD Type S w/Advance Package, SH-AWD w/A-SPEC, SH-AWD w/Advance, SH-AWD w/Tech, w/Tech
2022 Lexus RX 350L Trim Levels
Base, Luxury
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years / 50000 miles
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2026 NHTSA Overall Rating:
4 out of 5 Stars
2026 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2026 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2026 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
4 out of 5 Stars
2026 NHTSA Overall Rating:
4 out of 5 Stars
2026 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2026 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2026 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Base Drivetrain Specs
Horsepower:
290 hp @ 6200 rpm
Torque:
267 foot-lbs @ 4700 rpm
Power-to-Weight Ratio (higher is better):
0.068 hp per pound
Towing capacity:
Not yet available
Base Drivetrain Specs
Horsepower:
290 hp @ 6300 rpm
Torque:
263 foot-lbs @ 4700 rpm
Power-to-Weight Ratio (higher is better):
0.065 hp per pound
Towing capacity:
Not yet available
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
19 / 26 / 22
Range (city/hwy):
352 / 481 miles
Recommended Fuel Type:
Premium Unleaded
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
19 / 26 / 22
Range (city/hwy):
365 / 499 miles
Recommended Fuel Type:
Regular Unleaded
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Sunroof/Moonroof:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Wireless Smartphone Charging:
Standard
Air Suspension:
Available
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Massage Seats:
Available
Navigation System:
Available
Parking Sensors:
Available
Roof Rack:
Available
Trailer Hitch:
Available
Automatic Parking:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Internet Radio:
N/A
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Available
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Sunroof/Moonroof:
Available
Voice Recognition:
Standard
Wifi:
Standard
Wireless Smartphone Charging:
Available
Air Suspension:
N/A
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Massage Seats:
N/A
Navigation System:
Standard
Parking Sensors:
Available
Roof Rack:
Available
Trailer Hitch:
N/A
Automatic Parking:
N/A
Captain's seat:
Available
Front Bench Seats:
N/A
Internet Radio:
Standard
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
Available
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Driver Attention Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
Standard
360-Degree Camera:
Available
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Driver Attention Monitoring:
N/A
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
N/A
360-Degree Camera:
N/A
Interior Dimensions
Front Head Room:
38.5 inches
Front Leg Room:
41.6 inches
Front Shoulder Room:
61.9 inches
Rear Head Room:
38.1 inches
Rear Leg Room:
38.5 inches
Rear Shoulder Room:
60.3 inches
Cargo Space:
16.3 cubic feet
Cargo Space, 2nd-row seat folded down:
71.4 cubic feet
Overall Interior Volume:
155.4 cubic feet
Interior Dimensions
Front Head Room:
39.8 inches
Front Leg Room:
41.4 inches
Front Shoulder Room:
58.3 inches
Rear Head Room:
38.5 inches
Rear Leg Room:
30.9 inches
Rear Shoulder Room:
57.8 inches
Cargo Space:
7.5 cubic feet
Cargo Space, 2nd-row seat folded down:
58.5 cubic feet
Overall Interior Volume:
124.5 cubic feet
Exterior Dimensions
Curb Weight:
4271 lbs
Width:
78.7 inches
Height:
67.1 inches
Length:
198.4 inches
Wheelbase:
113.8 inches
Ground Clearance:
7.3 inches
Exterior Dimensions
Curb Weight:
4464 lbs
Width:
74.6 inches
Height:
67.3 inches
Length:
196.9 inches
Wheelbase:
109.8 inches
Ground Clearance:
8.1 inches
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.5 inches
Wheel Type:
aluminum alloy
Tire Size:
255/55R19
Standard Wheel/Tire Information
Wheel Size:
18.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/65R18
Exterior Colors
Black
Majestic Black Pearl
Blue
Fathom Blue Pearl
Gray
Liquid Carbon Metallic
Red
Performance Red Pearl
Silver
Lunar Silver Metallic
White
Platinum White Pearl
Green
Not available
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Cloudburst Gray
Red
Matador Red Mica
Silver
Iridium
White
Eminent White Pearl
Green
Nori Green Pearl
Interior Colors
Beige
Parchment
Black
Ebony
Brown
Not available
Gray
Not available
Interior Colors
Beige
Parchment w/Matte Bamboo Trim / Parchment w/Striated Black Trim
Black
Black w/Open Pore Black Walnut Trim and Blue Stitching / Black w/Open-Pore Brown Walnut Trim / Black w/Striated Black Trim
Brown
Glazed Carmel w/Open-Pore Brown Walnut Trim
Gray
Birch w/Open-Pore Brown Walnut Trim / Birch w/Striated Black Trim

