Acura MDX vs. Lexus IS 350
iSeeCars' unbiased and data-driven comparison of the Acura MDX and Lexus IS 350 contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the Acura MDX and the Lexus IS 350.
In comparing the Acura MDX's and the Lexus IS 350's specifications and ratings, the Acura MDX has the advantage in the areas of interior volume and overall quality score. The Lexus IS 350 has the advantage in the areas of new vehicle base pricing, typical lower range of pricing for one- to five-year-old used cars, reliability, resale value and base engine power. Based on this comparison of the Acura MDX's and the Lexus IS 350's specifications and ratings, the Lexus IS 350 is a better car than the Acura MDX.
Pricing: A used 2026 Acura MDX ranges from $55,350 to $70,850 while a used 2025 Lexus IS 350 is priced between $42,935 to $56,980. For a new model, the Acura MDX's price is between $55,950 and $77,785, with the Lexus IS 350 priced between $46,323 and $56,587.
Resale/Retained Value: Looking at the 5-year depreciation rate for both models, the Acura MDX loses 53.7 percent of its value and the Lexus IS 350 loses 39.2 percent of its value. This means the Lexus IS 350 retains 14.5 percentage points more of its value and has the advantage of higher resale value versus the Acura MDX.
Quality Rating: The iSeeCars Overall Quality rating for the Acura MDX is 8.5 out of 10 while the Lexus IS 350's quality rating is 8.3 out of 10. This results in the Acura MDX being ranked 1 out of 68 Best Luxury Crossover SUVs and the Lexus IS 350 being ranked 2 out of 36 Best Luxury Small Cars.
Reliability Rating: iSeeCars’ Reliability Rating for the Acura MDX is 8.0 out of 10. For the Lexus IS 350 the reliability rating is 8.5 out of 10. This gives the Lexus IS 350 a slight advantage in reliability compared to the Acura MDX.
Engine Power and Fuel Efficiency Comparison: For engine performance, the Acura MDX’s base engine makes 290 horsepower, and the Lexus IS 350 base engine makes 311 horsepower.
Passenger Space Comparison: The Acura MDX, a crossover/midsize SUV, has the advantage of offering more interior volume, reflected in more front head room, front shoulder room, rear head room, rear shoulder room, rear leg room, and cargo space. The Lexus IS 350, a compact car, has the advantage in the area of front leg room.
Safety Ratings: When comparing crash test ratings from NHTSA, both the Acura MDX and the Lexus IS 350 have the same average safety rating of 5 out of 5 Stars.
New Car Pricing
Asking Price:
55950 - 77785
Starting MSRP:
51800
Category Avg Starting MSRP:
(Luxury Midsize SUVs)
77833
Category Starting MSRP Range:
(Luxury Midsize SUVs)
51200 - 138300
New Car Pricing
Asking Price:
46323 - 56587
Starting MSRP:
43860
Category Avg Starting MSRP:
(Luxury Compact Cars)
49451
Category Starting MSRP Range:
(Luxury Compact Cars)
33000 - 79900
Used Car Pricing
Avg Used Car Price:
66659
Price Range:
55350 - 70850
Category Avg Price:
(Luxury Midsize SUVs)
73712
Category Avg Price Range:
(Luxury Midsize SUVs)
60234 - 92425
# Used Cars for Sale Nationally:
Avg Mileage of Used Cars for Sale:
# Good or Great Deals:
Used Car Pricing
Avg Used Car Price:
48858
Price Range:
42935 - 56980
Category Avg Price:
(Luxury Compact Cars)
51959
Category Avg Price Range:
(Luxury Compact Cars)
34107 - 95081
# Used Cars for Sale Nationally:
Avg Mileage of Used Cars for Sale:
# Good or Great Deals:
5-year Depreciation
Depreciation $:
27937
Depreciation %:
0.53931912
Resale Value $:
23863
Residual Value %:
0.46068087999999996
Typical Category Depreciation %:
(Luxury Midsize SUVs)
0.56208052
Category Depreciation Range:
(Luxury Midsize SUVs)
0.41556056 - 0.61479035
5-year Depreciation
Depreciation $:
17273
Depreciation %:
0.3938158
Resale Value $:
26587
Residual Value %:
0.6061842
Typical Category Depreciation %:
(Luxury Compact Cars)
0.51356376
Category Depreciation Range:
(Luxury Compact Cars)
0.34749831 - 0.55942423
Acura MDX Scores & Rankings
Overall Score:
8.5 / 10
Reliability:
8.0 / 10
Retained Value:
7.6 / 10
Safety:
10.0 / 10
Lexus IS 350 Scores & Rankings
Overall Score:
8.3 / 10
Reliability:
8.5 / 10
Retained Value:
8.5 / 10
Safety:
8.0 / 10
iSeeCars Reliability Insights for Acura MDX
Avg Life Expectancy (years):
13.1
Typical Category Life Expectancy:
(Luxury Midsize SUVs)
12.8
Category Life Expectancy Range:
(Luxury Midsize SUVs)
9.7 - 13.1
Chance of Reaching 200k Miles for a New Car:
0.317
iSeeCars Reliability Insights for Lexus IS 350
Avg Life Expectancy (years):
20.1
Typical Category Life Expectancy:
(Luxury Compact Cars)
11.0
Category Life Expectancy Range:
(Luxury Compact Cars)
9.5 - 20.1
Chance of Reaching 200k Miles for a New Car:
0.517
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
Typical Category Recalls:
N/A
Category Range for Recalls:
N/A
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.4871081513187803
Typical Category Recalls:
(Luxury Compact Cars)
2.2
Category Range for Recalls:
(Luxury Compact Cars)
1.5 - 10.4
Acura MDX Rankings
Ranking
1 out of / 68Ranking
1 out of / 68Ranking
1 out of / 29Ranking
1 out of / 27Ranking
1 out of / 27Ranking
1 out of / 13Ranking
1 out of / 13Ranking
1 out of / 8Ranking
1 out of / 7Ranking
2 out of / 8Ranking
2 out of / 7Ranking
3 out of / 29Ranking
3 out of / 25Ranking
3 out of / 25Ranking
5 out of / 26Ranking
6 out of / 29Ranking
6 out of / 27Ranking
7 out of / 68Ranking
9 out of / 29Ranking
9 out of / 27Ranking
10 out of / 27Ranking
12 out of / 27Ranking
13 out of / 68Ranking
14 out of / 27Ranking
17 out of / 29Ranking
17 out of / 27Ranking
18 out of / 68Ranking
18 out of / 29Ranking
19 out of / 27Ranking
19 out of / 27Ranking
20 out of / 29Ranking
22 out of / 29Ranking
22 out of / 29Ranking
23 out of / 68Ranking
23 out of / 29Ranking
23 out of / 27Ranking
24 out of / 29Ranking
27 out of / 68Ranking
33 out of / 64Ranking
34 out of / 68Ranking
39 out of / 68Ranking
48 out of / 68Ranking
49 out of / 68Lexus IS 350 Rankings
Ranking
1 out of / 36Ranking
1 out of / 32Ranking
2 out of / 36Ranking
2 out of / 36Ranking
4 out of / 36Ranking
5 out of / 36Ranking
11 out of / 32Ranking
19 out of / 36Ranking
21 out of / 36Ranking
28 out of / 36Available Body Styles
SUV
Available Body Styles
Sedan
Available Drivetrain Options
Gasoline
Available Drivetrain Options
Gasoline
Acura MDX Trim Levels
Base, SH-AWD, SH-AWD w/A-SPEC w/Advance, SH-AWD Type S w/Advance Package, SH-AWD w/A-SPEC, SH-AWD w/Advance, SH-AWD w/Tech, w/Tech
Lexus IS 350 Trim Levels
F SPORT, F SPORT Design
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years / 50000 miles
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2025 NHTSA Overall Rating:
Not yet available
2025 NHTSA Front Crash Overall Rating:
Not yet available
2025 NHTSA Side Crash Overall Rating:
Not yet available
2025 NHTSA Rollover Rating:
Not yet available
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2025 NHTSA Overall Rating:
5 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
5 out of 5 Stars
IIHS Safety Rating:
Not yet available
Base Drivetrain Specs
Horsepower:
290 hp @ 6200 rpm
Torque:
267 foot-lbs @ 4700 rpm
Power-to-Weight Ratio (higher is better):
0.068 hp per pound
Towing capacity:
Not yet available
Base Drivetrain Specs
Horsepower:
311 hp @ 6600 rpm
Torque:
280 foot-lbs @ 4800 rpm
Power-to-Weight Ratio (higher is better):
0.083 hp per pound
Towing capacity:
Not yet available
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
FWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
Not yet available
Range (city/hwy):
Not yet available
Recommended Fuel Type:
Not yet available
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
RWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
20 / 28 / 23
Range (city/hwy):
348 / 487 miles
Recommended Fuel Type:
Premium Unleaded
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Standard
Paddle Shifters:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Sunroof/Moonroof:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Wireless Smartphone Charging:
Standard
Air Suspension:
Available
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Massage Seats:
Available
Parking Sensors:
Available
Roof Rack:
Available
Trailer Hitch:
Available
Automatic Parking:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Internet Radio:
N/A
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Satellite radio:
N/A
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Available
Paddle Shifters:
Standard
Power Lift Gate:
N/A
Power outlet:
Standard
Roadside assistance:
Standard
Sunroof/Moonroof:
Available
Voice Recognition:
Standard
Wifi:
Standard
Wireless Smartphone Charging:
N/A
Air Suspension:
N/A
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Standard
Massage Seats:
N/A
Parking Sensors:
Available
Roof Rack:
N/A
Trailer Hitch:
N/A
Automatic Parking:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Internet Radio:
Standard
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Satellite radio:
Standard
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Driver Attention Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
Standard
360-Degree Camera:
Available
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Driver Attention Monitoring:
N/A
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
N/A
360-Degree Camera:
N/A
Interior Dimensions
Front Head Room:
38.5 inches
Front Leg Room:
41.6 inches
Front Shoulder Room:
61.9 inches
Rear Head Room:
38.1 inches
Rear Leg Room:
38.5 inches
Rear Shoulder Room:
60.3 inches
Cargo Space:
16.3 cubic feet
Cargo Space, 2nd-row seat folded down:
71.4 cubic feet
Overall Interior Volume:
155.4 cubic feet
Interior Dimensions
Front Head Room:
38.2 inches
Front Leg Room:
44.8 inches
Front Shoulder Room:
55.9 inches
Rear Head Room:
36.9 inches
Rear Leg Room:
32.2 inches
Rear Shoulder Room:
53.4 inches
Cargo Space:
10.8 cubic feet
Cargo Space, 2nd-row seat folded down:
Not yet available
Overall Interior Volume:
90.2 cubic feet
Exterior Dimensions
Curb Weight:
4268 lbs
Width:
78.7 inches
Height:
67.9 inches
Length:
198.4 inches
Wheelbase:
113.8 inches
Ground Clearance:
7.3 inches
Exterior Dimensions
Curb Weight:
3748 lbs
Width:
72.4 inches
Height:
56.5 inches
Length:
185.4 inches
Wheelbase:
110.2 inches
Ground Clearance:
5.5 inches
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.5 inches
Wheel Type:
aluminum alloy
Tire Size:
255/55R19
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.5 inches
Wheel Type:
painted aluminum alloy
Tire Size:
235/40R19
Exterior Colors
Black
Majestic Black Pearl
Gray
Liquid Carbon Metallic
Silver
Solar Silver Metallic
White
Platinum White Pearl
Blue
Not available
Red
Not available
Exterior Colors
Black
Caviar
Gray
Cloudburst Gray / Incognito
Silver
Iridium
White
Ultra White
Blue
Ultrasonic Blue Mica 2.0
Red
Infrared
Interior Colors
Beige
Parchment
Black
Ebony
Brown
Not available
Red
Not available
Interior Colors
Beige
Not available
Black
Black w/ Black Metallic Trim
Brown
Glazed Caramel w/ Black Metallic Trim
Red
Rioja Red w/ Black Metallic Trim
