Mercedes-Benz 350-Class vs. Lexus IS 350
iSeeCars' unbiased and data-driven comparison of the Mercedes-Benz 350-Class and Lexus IS 350 contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the Mercedes-Benz 350-Class and the Lexus IS 350.
When comparing the Mercedes-Benz 350-Class's and the Lexus IS 350's specifications and ratings, The Lexus IS 350 has the advantage in the areas of fuel efficiency and base engine power. Based on this comparison of the Mercedes-Benz 350-Class's and the Lexus IS 350's specifications and ratings, the Lexus IS 350 is a better car than the Mercedes-Benz 350-Class.
Engine Power and Fuel Efficiency Comparison: For engine performance, the Mercedes-Benz 350-Class’s base engine makes 134 horsepower, and the Lexus IS 350 base engine makes 311 horsepower. The 350-Class is rated to deliver an average of 21 miles per gallon, with a highway range of 529 miles. The IS 350 is rated to deliver an average of 23 miles per gallon, with a highway range of 487 miles.This gives the Lexus IS 350 the advantage in fuel efficiency and the Mercedes-Benz 350-Class the advantage in maximum range. The 350-Class uses diesel, and the IS 350 uses premium unleaded.
Safety Ratings: The Lexus IS 350 has an average safety rating of 5 out of 5 Stars based on NHTSA's crash test ratings.
New Car Pricing
Asking Price:
-
Starting MSRP:
54250
Category Avg Starting MSRP:
N/A
Category Starting MSRP Range:
N/A
New Car Pricing
Asking Price:
46323 - 56587
Starting MSRP:
43860
Category Avg Starting MSRP:
(Luxury Compact Cars)
49451
Category Starting MSRP Range:
(Luxury Compact Cars)
33000 - 79900
Used Car Pricing
Avg Used Car Price:
Price Range:
-
Category Avg Price:
N/A
Category Avg Price Range:
N/A
# Used Cars for Sale Nationally:
1
Avg Mileage of Used Cars for Sale:
90083
# Good or Great Deals:
0
Used Car Pricing
Avg Used Car Price:
48858
Price Range:
42935 - 56980
Category Avg Price:
(Luxury Compact Cars)
51959
Category Avg Price Range:
(Luxury Compact Cars)
34107 - 95081
# Used Cars for Sale Nationally:
Avg Mileage of Used Cars for Sale:
# Good or Great Deals:
Mercedes-Benz 350-Class Scores & Rankings
Overall Score:
Not available
Reliability:
Not available
Retained Value:
Not available
Safety:
Not available
Lexus IS 350 Scores & Rankings
Overall Score:
8.3 / 10
Reliability:
8.5 / 10
Retained Value:
8.5 / 10
Safety:
8.0 / 10
iSeeCars Reliability Insights for Mercedes-Benz 350-Class
Remaining Life Expectancy (years):
Typical Category Remaining Life Expectancy:
N/A
Category Remaining Life Expectancy Range:
N/A
Chance of Reaching 200k Miles for a New Car:
iSeeCars Reliability Insights for Lexus IS 350
Avg Life Expectancy (years):
20.1
Typical Category Life Expectancy:
(Luxury Compact Cars)
11.0
Category Life Expectancy Range:
(Luxury Compact Cars)
9.5 - 20.1
Chance of Reaching 200k Miles for a New Car:
0.517
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
Typical Category Recalls:
N/A
Category Range for Recalls:
N/A
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.4871081513187803
Typical Category Recalls:
(Luxury Compact Cars)
2.2
Category Range for Recalls:
(Luxury Compact Cars)
1.5 - 10.4
Mercedes-Benz 350-Class Rankings
Not yet available
Lexus IS 350 Rankings
Ranking
1 out of / 35Ranking
2 out of / 35Ranking
2 out of / 35Ranking
2 out of / 35Ranking
3 out of / 35Ranking
3 out of / 30Ranking
5 out of / 35Ranking
11 out of / 30Ranking
21 out of / 35Ranking
22 out of / 35Ranking
26 out of / 35Ranking
28 out of / 35Available Body Styles
Sedan
Available Body Styles
Sedan
Available Drivetrain Options
Diesel
Available Drivetrain Options
Gasoline
Mercedes-Benz 350-Class Trim Levels
350 SD, 350 SDL
Lexus IS 350 Trim Levels
F SPORT, F SPORT Design
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
4 years / 50000 miles
Warranty, Roadside Assistance:
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Safety Ratings
NHTSA Safety Rating (last 5 year average):
Not yet available
2026 NHTSA Overall Rating:
Not yet available
2026 NHTSA Front Crash Overall Rating:
Not yet available
2026 NHTSA Side Crash Overall Rating:
Not yet available
2026 NHTSA Rollover Rating:
Not yet available
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2026 NHTSA Overall Rating:
5 out of 5 Stars
2026 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2026 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2026 NHTSA Rollover Rating:
5 out of 5 Stars
IIHS Safety Rating:
Not yet available
Base Drivetrain Specs
Horsepower:
134 hp @ 4000 rpm
Torque:
229 foot-lbs @ 2000 rpm
Power-to-Weight Ratio (higher is better):
0.035 hp per pound
Base Drivetrain Specs
Horsepower:
311 hp @ 6600 rpm
Torque:
280 foot-lbs @ 4800 rpm
Power-to-Weight Ratio (higher is better):
0.083 hp per pound
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
Inline
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
RWD
EPA Fuel Economy
(City/Highway/Combined MPG):
19 / 23 / 21
Range (city/hwy):
437 / 529 miles
Recommended Fuel Type:
Diesel
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Automatic
Standard/Optional Drivetrain Type:
RWD / AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
20 / 28 / 23
Range (city/hwy):
348 / 487 miles
Recommended Fuel Type:
Premium Unleaded
Standard/Optional Features
Alloy wheels:
Standard
Heated Seats
Available
Leather Upholstery:
Available
Sunroof/Moonroof:
Available
Adaptive Cruise Control:
N/A
Air Suspension:
N/A
Android Auto:
N/A
Apple CarPlay:
N/A
Automatic Parking:
N/A
Bench Seats:
N/A
Bluetooth:
N/A
Captain's seat:
N/A
Cooled/Ventilated Seats:
N/A
Front Bench Seats:
N/A
Heated Steering Wheel:
N/A
Internet Radio:
N/A
Keyless Entry:
N/A
Keyless Ignition:
N/A
Massage Seats:
N/A
Navigation System:
N/A
Paddle Shifters:
N/A
Panoramic Sunroof/Moonroof
N/A
Parking Sensors:
N/A
Power Lift Gate:
N/A
Power outlet:
N/A
Quad Seats:
N/A
Roadside assistance:
N/A
Roof Rack:
N/A
Satellite radio:
N/A
Trailer Hitch:
N/A
Voice Recognition:
N/A
Wifi:
N/A
Wireless Smartphone Charging:
N/A
Standard/Optional Features
Alloy wheels:
Standard
Heated Seats
Standard
Leather Upholstery:
Standard
Sunroof/Moonroof:
Available
Adaptive Cruise Control:
Standard
Air Suspension:
N/A
Android Auto:
Standard
Apple CarPlay:
Standard
Automatic Parking:
N/A
Bench Seats:
Standard
Bluetooth:
Standard
Captain's seat:
N/A
Cooled/Ventilated Seats:
Available
Front Bench Seats:
N/A
Heated Steering Wheel:
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Massage Seats:
N/A
Navigation System:
Available
Paddle Shifters:
Standard
Panoramic Sunroof/Moonroof
N/A
Parking Sensors:
Available
Power Lift Gate:
N/A
Power outlet:
Standard
Quad Seats:
N/A
Roadside assistance:
Standard
Roof Rack:
N/A
Satellite radio:
Standard
Trailer Hitch:
N/A
Voice Recognition:
Standard
Wifi:
Standard
Wireless Smartphone Charging:
N/A
Safety Features
360-Degree Camera:
N/A
Backup camera:
N/A
Blind Spot Monitoring:
N/A
Driver Attention Monitoring:
N/A
Forward Collision Warning:
N/A
Lane Departure Warning:
N/A
Lane Keeping Assist:
N/A
Pedestrian Detection:
N/A
Rear Cross-Traffic Alert:
N/A
Rear Seat Reminder:
N/A
Safety Features
360-Degree Camera:
N/A
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Driver Attention Monitoring:
N/A
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
N/A
Interior Dimensions
Front Head Room:
37.2 inches
Front Leg Room:
41.9 inches
Front Shoulder Room:
56.2 inches
Rear Head Room:
36.5 inches
Rear Leg Room:
33.4 inches
Rear Shoulder Room:
55.7 inches
Cargo Space:
Not yet available
Overall Interior Volume:
Not yet available
Interior Dimensions
Front Head Room:
38.2 inches
Front Leg Room:
44.8 inches
Front Shoulder Room:
55.9 inches
Rear Head Room:
36.9 inches
Rear Leg Room:
32.2 inches
Rear Shoulder Room:
53.4 inches
Cargo Space:
10.8 cubic feet
Overall Interior Volume:
90.2 cubic feet
Exterior Dimensions
Curb Weight:
3805 lbs
Width:
71.7 inches
Height:
56.6 inches
Length:
202.6 inches
Wheelbase:
115.6 inches
Ground Clearance:
Not yet available
Exterior Dimensions
Curb Weight:
3748 lbs
Width:
72.4 inches
Height:
56.5 inches
Length:
185.4 inches
Wheelbase:
110.2 inches
Ground Clearance:
5.5 inches
Standard Wheel/Tire Information
Wheel Size:
15.0 inches
Wheel Type:
aluminum alloy
Tire Size:
Not yet available
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.5 inches
Wheel Type:
painted aluminum alloy
Tire Size:
235/40R19
Exterior Colors
Black
Black / Black Pearl Metallic
Blue
Ice Blue Metallic
Brown
Desert Taupe Metallic
Gray
Anthracite Gray Metallic / Pearl Gray Metallic
Green
Seafoam Green Metallic / Spruce Green Metallic
Purple
Blackberry Metallic
Red
Desert Red / Garnet Red Metallic
White
Arctic White
Silver
Not available
Exterior Colors
Black
Caviar
Blue
Ultrasonic Blue Mica 2.0
Brown
Not available
Gray
Cloudburst Gray / Incognito
Green
Not available
Purple
Not available
Red
Infrared
White
Ultra White
Silver
Iridium
Interior Colors
Black
Not available
Brown
Not available
Red
Not available
Interior Colors
Black
Black w/ Black Metallic Trim
Brown
Glazed Caramel w/ Black Metallic Trim
Red
Rioja Red w/ Black Metallic Trim
