Lexus RX 350h vs. Lexus RX 450h
iSeeCars' unbiased and data-driven comparison of the Lexus RX 350h and Lexus RX 450h contrasts the two cars across a broad spectrum of vehicle specifications to determine which car is better. In addition to comparing pricing and specs, iSeeCars uses all the ratings, rankings, and insights from its comprehensive analyses of each vehicle model, including calculations of reliability, safety, depreciation, value retention, and the vehicle's projected lifetime recalls (based on analyzing over 25 billion data points). This in-depth evaluation is used to identify which vehicle represents a better overall choice for shoppers who are considering both the Lexus RX 350h and the Lexus RX 450h.
When comparing the Lexus RX 350h's and the Lexus RX 450h's specifications and ratings, the Lexus RX 350h has the advantage in the areas of fuel efficiency and overall quality score. The Lexus RX 450h has the advantage in the areas of typical lower range of pricing for one- to five-year-old used cars, resale value and base engine power. The Lexus RX 350h and Lexus RX 450h have the same Based on this comparison of the Lexus RX 350h's and the Lexus RX 450h's specifications and ratings, the Lexus RX 450h is a better car than the Lexus RX 350h.
Pricing: A used 2025 Lexus RX 350h ranges from $55,900 to $69,992 while a used 2022 Lexus RX 450h is priced between $39,998 to $54,414.
Resale/Retained Value: Looking at the 5-year depreciation rate for both models, the Lexus RX 350h loses 43.8 percent of its value and the Lexus RX 450h loses 40.6 percent of its value. This means the Lexus RX 450h retains 3.3 percentage points more of its value and has the advantage of higher resale value versus the Lexus RX 350h.
Quality Rating: The iSeeCars Overall Quality rating for the Lexus RX 350h is 8.3 out of 10 while the Lexus RX 450h's quality rating is 8.1 out of 10. This results in the Lexus RX 350h being ranked 1 out of 32 Best Luxury Hybrid SUVs and the Lexus RX 450h being ranked 3 out of 32. Out of 29 Best Hybrid Luxury Crossover SUVs, the Lexus RX 350h is ranked 1 and the Lexus RX 450h is ranked 3. The Lexus RX 350h is also ranked 1 out of 12 Best Hybrid Luxury Midsize SUVs while the Lexus RX 450h is ranked 3 out of 12.
Reliability Rating: iSeeCars' Reliability Rating for the Lexus RX 350h and Lexus RX 450h is 8.6 out of 10.
Engine Power and Fuel Efficiency Comparison: For engine performance, the Lexus RX 350h’s base engine makes 246 horsepower, and the Lexus RX 450h base engine makes 308 horsepower. The RX 350h is rated to deliver an average of 36 miles per gallon, with a highway range of 585 miles. The RX 450h is rated to deliver an average of 30 miles per gallon, with a highway range of 482 miles. This gives the Lexus RX 350h the fuel efficiency and maximum range advantage over the Lexus RX 450h. Both models use premium unleaded.
Safety Ratings: When comparing crash test ratings from NHTSA, the Lexus RX 350h has higher safety ratings than the Lexus RX 450h, with an average rating of 5 out of 5 Stars compared to 4.45 out of 5 Stars.
New Car Pricing
Asking Price:
57462 - 69784
Starting MSRP:
51125
Category Avg Starting MSRP:
(Luxury Hybrid Midsize SUVs)
72193
Category Starting MSRP Range:
(Luxury Hybrid Midsize SUVs)
51125 - 97200
New Car Pricing
Asking Price:
-
Starting MSRP:
48720
Category Avg Starting MSRP:
(Luxury Hybrid Midsize SUVs)
61958
Category Starting MSRP Range:
(Luxury Hybrid Midsize SUVs)
48720 - 83300
Used Car Pricing
Avg Used Car Price:
62087
Price Range:
55900 - 69992
Category Avg Price:
(Luxury Hybrid Midsize SUVs)
81631
Category Avg Price Range:
(Luxury Hybrid Midsize SUVs)
60560 - 138586
# Used Cars for Sale Nationally:
Avg Mileage of Used Cars for Sale:
# Good or Great Deals:
Used Car Pricing
Avg Used Car Price:
47423
Price Range:
39998 - 54414
Category Avg Price:
(Luxury Hybrid Midsize SUVs)
56642
Category Avg Price Range:
(Luxury Hybrid Midsize SUVs)
47423 - 82654
# Used Cars for Sale Nationally:
132
Avg Mileage of Used Cars for Sale:
41843
# Good or Great Deals:
35
Lexus RX 350h Scores & Rankings
Overall Score:
8.3 / 10
Reliability:
8.6 / 10
Retained Value:
8.2 / 10
Safety:
8.0 / 10
Lexus RX 450h Scores & Rankings
Overall Score:
8.1 / 10
Reliability:
8.6 / 10
Retained Value:
8.4 / 10
Safety:
7.4 / 10
iSeeCars Reliability Insights for Lexus RX 350h
Avg Life Expectancy (years):
18.1
Typical Category Life Expectancy:
(Luxury Hybrid Midsize SUVs)
18.1
Category Life Expectancy Range:
(Luxury Hybrid Midsize SUVs)
18.1 - 18.1
Chance of Reaching 200k Miles for a New Car:
0.44
iSeeCars Reliability Insights for Lexus RX 450h
Remaining Life Expectancy (years):
15.1
Typical Category Remaining Life Expectancy:
(Luxury Hybrid Midsize SUVs)
15.1
Category Remaining Life Expectancy Range:
(Luxury Hybrid Midsize SUVs)
15.1 - 15.1
Chance of Reaching 200k Miles for a New Car:
0.44
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.524212686978769
Typical Category Recalls:
(Luxury Hybrid Midsize SUVs)
2.7
Category Range for Recalls:
(Luxury Hybrid Midsize SUVs)
1.5 - 11.3
Expected 30-year Lifetime Recalls
Expected Lifetime Recalls:
1.0995134697947773
Typical Category Recalls:
(Luxury Hybrid Midsize SUVs)
3.4
Category Range for Recalls:
(Luxury Hybrid Midsize SUVs)
1.1 - 7.3
Lexus RX 350h Rankings
Ranking
1 out of / 32Ranking
1 out of / 32Ranking
1 out of / 32Ranking
1 out of / 29Ranking
1 out of / 29Ranking
1 out of / 12Ranking
1 out of / 12Ranking
1 out of / 10Ranking
1 out of / 10Ranking
1 out of / 10Ranking
1 out of / 10Ranking
1 out of / 9Ranking
1 out of / 4Ranking
1 out of / 4Ranking
5 out of / 26Ranking
5 out of / 23Ranking
5 out of / 12Ranking
5 out of / 12Ranking
5 out of / 12Ranking
6 out of / 12Ranking
6 out of / 12Ranking
6 out of / 12Ranking
9 out of / 12Ranking
10 out of / 32Ranking
10 out of / 29Ranking
10 out of / 29Ranking
11 out of / 32Ranking
11 out of / 29Ranking
12 out of / 12Ranking
13 out of / 32Ranking
13 out of / 32Ranking
13 out of / 29Ranking
13 out of / 29Ranking
14 out of / 29Ranking
15 out of / 32Ranking
17 out of / 32Ranking
24 out of / 29Ranking
25 out of / 29Ranking
27 out of / 32Ranking
28 out of / 32Lexus RX 450h Rankings
Ranking
1 out of / 32Ranking
1 out of / 29Ranking
1 out of / 12Ranking
1 out of / 12Ranking
3 out of / 32Ranking
3 out of / 32Ranking
3 out of / 29Ranking
3 out of / 12Ranking
4 out of / 32Ranking
4 out of / 29Ranking
4 out of / 12Ranking
6 out of / 12Ranking
7 out of / 29Ranking
7 out of / 12Ranking
8 out of / 32Ranking
8 out of / 12Ranking
8 out of / 12Ranking
12 out of / 32Ranking
12 out of / 29Ranking
12 out of / 29Ranking
12 out of / 12Ranking
15 out of / 32Ranking
16 out of / 29Ranking
16 out of / 29Ranking
19 out of / 32Ranking
19 out of / 32Ranking
27 out of / 29Ranking
30 out of / 32Available Body Styles
SUV
Available Body Styles
SUV
Available Drivetrain Options
Hybrid
Available Drivetrain Options
Hybrid
Lexus RX 350h Trim Levels
Base, F SPORT Design, Luxury, Premium, Premium+
Lexus RX 450h Trim Levels
Base, F SPORT, F SPORT Handling
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Warranty Information
Warranty, Bumper-to-Bumper:
4 years / 50000 miles
Warranty, Powertrain:
6 years / 70000 miles
Warranty, Roadside Assistance:
4 years
Safety Ratings
NHTSA Safety Rating (last 5 year average):
5 out of 5 Stars
2025 NHTSA Overall Rating:
4 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Safety Ratings
NHTSA Safety Rating (last 5 year average):
4.45 out of 5 Stars
2025 NHTSA Overall Rating:
4 out of 5 Stars
2025 NHTSA Front Crash Overall Rating:
4 out of 5 Stars
2025 NHTSA Side Crash Overall Rating:
5 out of 5 Stars
2025 NHTSA Rollover Rating:
4 out of 5 Stars
IIHS Safety Rating:
Not yet available
Base Drivetrain Specs
Horsepower:
246 hp @ 6000 rpm
Torque:
233 foot-lbs @ 4300 rpm
Power-to-Weight Ratio (higher is better):
0.055 hp per pound
Towing capacity:
Not yet available
Base Drivetrain Specs
Horsepower:
308 hp @ 6000 rpm
Torque:
Not yet available
Power-to-Weight Ratio (higher is better):
0.065 hp per pound
Towing capacity:
Not yet available
Engine Specifications
Engine Size:
2.5 liters
Engine Configuration:
Inline
Number of Cylinders:
4
Transmission:
Continuously Variable Transmission (CVT Automatic)
Standard/Optional Drivetrain Type:
AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
37 / 34 / 36
Range (city/hwy):
636 / 585 miles
Recommended Fuel Type:
Premium Unleaded
Engine Specifications
Engine Size:
3.5 liters
Engine Configuration:
V
Number of Cylinders:
6
Transmission:
Continuously Variable Transmission (CVT Automatic)
Standard/Optional Drivetrain Type:
AWD
EPA Fuel Economy
(City/Highway/Combined MPG):
31 / 28 / 30
Range (city/hwy):
533 / 482 miles
Recommended Fuel Type:
Premium Unleaded
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Standard
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Standard
Paddle Shifters:
Standard
Parking Sensors:
Standard
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Automatic Parking:
Available
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Roof Rack:
Available
Sunroof/Moonroof:
Available
Trailer Hitch:
Available
Wireless Smartphone Charging:
Available
Air Suspension:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Standard/Optional Features
Adaptive Cruise Control:
Standard
Alloy wheels:
Standard
Android Auto:
Standard
Apple CarPlay:
Standard
Bench Seats:
Standard
Bluetooth:
Standard
Heated Seats
Available
Internet Radio:
Standard
Keyless Entry:
Standard
Keyless Ignition:
Standard
Leather Upholstery:
Standard
Navigation System:
Standard
Paddle Shifters:
Standard
Parking Sensors:
Available
Power Lift Gate:
Standard
Power outlet:
Standard
Roadside assistance:
Standard
Satellite radio:
Standard
Voice Recognition:
Standard
Wifi:
Standard
Automatic Parking:
N/A
Cooled/Ventilated Seats:
Available
Heated Steering Wheel:
Available
Roof Rack:
Available
Sunroof/Moonroof:
Available
Trailer Hitch:
N/A
Wireless Smartphone Charging:
Available
Air Suspension:
N/A
Captain's seat:
N/A
Front Bench Seats:
N/A
Massage Seats:
N/A
Panoramic Sunroof/Moonroof
N/A
Quad Seats:
N/A
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
Standard
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Safety Features
Backup camera:
Standard
Blind Spot Monitoring:
Standard
Forward Collision Warning:
Standard
Lane Departure Warning:
Standard
Lane Keeping Assist:
Standard
Pedestrian Detection:
Standard
Rear Cross-Traffic Alert:
Standard
Rear Seat Reminder:
N/A
360-Degree Camera:
N/A
Driver Attention Monitoring:
N/A
Interior Dimensions
Front Head Room:
39.5 inches
Front Leg Room:
41.1 inches
Front Shoulder Room:
58.1 inches
Rear Head Room:
38.6 inches
Rear Leg Room:
37.4 inches
Rear Shoulder Room:
56.5 inches
Cargo Space:
29.6 cubic feet
Cargo Space, 2nd-row seat folded down:
46.2 cubic feet
Overall Interior Volume:
Not yet available
Interior Dimensions
Front Head Room:
39.4 inches
Front Leg Room:
44.1 inches
Front Shoulder Room:
57.8 inches
Rear Head Room:
38.2 inches
Rear Leg Room:
38 inches
Rear Shoulder Room:
57.6 inches
Cargo Space:
16 cubic feet
Cargo Space, 2nd-row seat folded down:
32.6 cubic feet
Overall Interior Volume:
114.1 cubic feet
Exterior Dimensions
Curb Weight:
4455 lbs
Width:
75.6 inches
Height:
67.3 inches
Length:
192.5 inches
Wheelbase:
112.2 inches
Ground Clearance:
8.2 inches
Exterior Dimensions
Curb Weight:
4740 lbs
Width:
74.6 inches
Height:
67.7 inches
Length:
192.5 inches
Wheelbase:
109.8 inches
Ground Clearance:
8.2 inches
Standard Wheel/Tire Information
Wheel Size:
19.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/60R19
Standard Wheel/Tire Information
Wheel Size:
18.0 x 8.0 inches
Wheel Type:
aluminum alloy
Tire Size:
235/65R18
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Cloudburst Gray
Green
Nori Green Pearl
Red
Matador Red Mica
Silver
Iridium
White
Eminent White Pearl
Exterior Colors
Black
Caviar
Blue
Nightfall Mica
Gray
Nebula Gray Pearl
Green
Nori Green Pearl
Red
Matador Red Mica
Silver
Atomic Silver
White
Eminent White Pearl
Interior Colors
Black
Black w/ Black Cascade Trim
Brown
Palamino w/ Black Cascade Trim
Beige
Not available
Gray
Not available
Interior Colors
Black
Black w/Gray Sapele Wood and Aluminum Trim / Black w/Matte Walnut Trim / Black w/Open Pore Black Walnut Trim and White Accents and Gray Stitching / Black w/Striated Black Trim
Brown
Glazed Caramel w/Gray Sapele Wood and Aluminum Trim / Glazed Caramel w/Matte Walnut Trim
Beige
Parchment w/Gray Sapele Wood and Aluminum Trim / Parchment w/Matte Bamboo Trim / Parchment w/Striated Black Trim
Gray
Birch w/Gray Sapele Wood and Aluminum Trim / Birch w/Matte Walnut Trim / Birch w/Striated Black Trim