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| Model | 2021 Lexus IS 350 | 2021 Mercedes-Benz C-Class |
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| Body Styles | Sedan | Convertible, Coupe, Sedan |
| MSRP | $42,950 - $44,950 | $41,600 - $85,600 |
| Invoice | $39,945 - $41,805 | $39,104 - $80,464 |
| Gas Mileage | 22-24 mpg | 21-28 mpg |
| Specs | 2021 Lexus IS 350 Specs | 2021 Mercedes-Benz C-Class Specs |
| Transmission | A | A |
| Drivetrain | AWD, RWD | AWD, RWD |
| Engine Type | V6 | 4 Cylinder, 8 Cylinder, V6 |
| Fuel Type | Gasoline | Gasoline |
| Interior Features | 2021 Lexus IS 350 Interior Features | 2021 Mercedes-Benz C-Class Interior Features |
| Warranty | 2021 Lexus IS 350 Warranty | 2021 Mercedes-Benz C-Class Warranty |
| Safety Ratings | 2021 Lexus IS 350 Safety Ratings | 2021 Mercedes-Benz C-Class Safety Ratings |