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Best Used Luxury Midsize SUVs for 2026

These are the best used luxury midsize SUVs by price and budget based on a data-driven analysis of each vehicle's reliability, resale value and safety.

The best used luxury midsize SUV under $15k is the 2016 BMW X5, with the 2020 INFINITI QX60 being the best used luxury midsize SUV under $20k. The 2020 Mercedes-Benz GLE ranks #1 for the best used luxury midsize SUVs under $30k.

The best used luxury midsize SUV under $35k is the 2020 Lexus RX 350 and the best used luxury midsize SUV under $40k is the 2022 Acura MDX. Topping the list for the best used luxury midsize SUVs under $45k is the 2022 Mercedes-Benz GLE, while the 2023 Lexus RX 350 ranks first for the best used luxury midsize SUVs under $50k.

The best used luxury midsize SUV under $55k is the 2023 Mercedes-Benz GLE, with the 2023 Lexus GX 460 being the best used luxury midsize SUV under $60k.

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How We Rank These Cars

iSeeCars Best Used Car Rankings are calculated based on the latest research by our data science team and the National Highway Traffic Safety Administration (NHTSA).

We analyze data from over 12 million new and used vehicles in our Longest-Lasting Cars and 5-Year Depreciation Studies, combined with the NHTSA's Safety Ratings to give you an unbiased guide to the best vehicles in each segment.

After being evaluated, vehicles with the highest average scores earn a spot in the iSeeCars Best Car Rankings. (No final score is given to vehicles missing a score in any of the categories, but scores for other categories are still shown.)

Vehicles are scored in three categories:

Reliability

The reliability score represents an analysis of iSeeCars' proprietary research on the longest-lasting vehicles.

Value Retention

The value retention score is based on our data science team's statistical analysis and prediction of 5-year depreciation from MSRP to determine which cars hold their value best, using US Bureau of Labor Statistics data to adjust for inflation.

Safety

The safety score is calculated based on the last five years of crash test ratings from the National Highway Traffic Safety Administration (NHTSA) and incorporates the latest Top Safety Pick information from the Insurance Institute for Highway Safety (IIHS).