Best Luxury Midsize Cars with Android Auto for 2025
These are the best luxury midsize cars with Android Auto based on iSeeCars' analysis of each vehicle’s reliability, resale value and safety.
The best luxury midsize car with Android Auto is the Lexus ES 350 with an iSeeCars Score of 8.4 out of 10. The iSeeCars Score is calculated based on a vehicle’s reliability (based on iSeeCars’ proprietary analysis of a vehicle’s longevity), value retention (based on iSeeCars’ analysis of 5-year depreciation) and safety (based on NHTSA and IIHS safety ratings). The Android Auto feature is available either standard or optional on these cars. The second best luxury midsize car with Android Auto is the Mercedes-Benz E-Class with a rating of 8.2. In third place is the Mercedes-Benz E-Class (coupe) which has an iSeeCars Score of 8.0.
The best luxury midsize car with Android Auto is the Lexus ES 350 with an iSeeCars Score of 8.4 out of 10. The iSeeCars Score is calculated based on a vehicle’s reliability (based on iSeeCars’ proprietary analysis of a vehicle’s longevity), value retention (based on iSeeCars’ analysis of 5-year depreciation) and safety (based on NHTSA and IIHS safety ratings). The Android Auto feature is available either standard or optional on these cars. The second best luxury midsize car with Android Auto is the Mercedes-Benz E-Class with a rating of 8.2. In third place is the Mercedes-Benz E-Class (coupe) which has an iSeeCars Score of 8.0.
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Iseecars score
8.4
/ 10
- Starting MSRP: 42040
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
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Reliability
7.9
/ 10
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Value Retention
8.3
/ 10
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Safety
9.0
/ 10
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Iseecars score
8.2
/ 10
- Starting MSRP: 62450
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
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Reliability
8.2
/ 10
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Value Retention
7.3
/ 10
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Safety
9.0
/ 10
3. Mercedes-Benz E-Class (coupe)
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Iseecars score
8.0
/ 10
- Starting MSRP: 69750
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
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Reliability
8.3
/ 10
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Value Retention
7.7
/ 10
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Safety
Not Available
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Iseecars score
8.0
/ 10
- Starting MSRP: 42040
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.9
/ 10
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Value Retention
8.2
/ 10
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Safety
8.0
/ 10
5. Lincoln MKZ
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Iseecars score
7.8
/ 10
- Starting MSRP: 36750
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.8
/ 10
-
Value Retention
7.5
/ 10
-
Safety
8.0
/ 10
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.7
/ 10
-
Value Retention
7.8
/ 10
-
Safety
8.0
/ 10
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.5
/ 10
-
Value Retention
7.1
/ 10
-
Safety
8.0
/ 10
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.3
/ 10
-
Value Retention
7.3
/ 10
-
Safety
Not Available
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.3
/ 10
-
Value Retention
7.2
/ 10
-
Safety
Not Available
-
Iseecars score
7.2
/ 10
- Starting MSRP: 109500
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
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Reliability
7.4
/ 10
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Value Retention
6.9
/ 10
-
Safety
Not Available
-
Iseecars score
7.0
/ 10
- Starting MSRP: 58700
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
7.1
/ 10
-
Value Retention
7.0
/ 10
-
Safety
7.0
/ 10
-
Iseecars score
Not Available
- Starting MSRP: 99750
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
8.5
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 48600
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
8.1
/ 10
-
Safety
8.0
/ 10
-
Iseecars score
Not Available
- Starting MSRP: 57600
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.9
/ 10
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Safety
8.0
/ 10
Buick Regal Sportback
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Iseecars score
Not Available
- Starting MSRP: 25370
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.7
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 91700
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.6
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 57100
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.5
/ 10
-
Safety
10
/ 10
-
Iseecars score
Not Available
- Starting MSRP: 75900
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.3
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 85700
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.3
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 58300
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.3
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 140000
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.2
/ 10
-
Safety
Not Available
-
Iseecars score
Not Available
- Starting MSRP: 90800
iSEECARS SCORE
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars
-
Reliability
Coming soon
-
Value Retention
7.1
/ 10
-
Safety
Not Available
Related Rankings
How We Rank These Cars
The Best Cars with Android Auto list ranks vehicles by their iSeeCars Score, which is based on our proprietary assessment of a vehicle’s reliability, resale value and safety (based on ratings from IIHS and NHTSA). The Android Auto feature is available either standard or optional on these cars.
The iSeeCars Score is an analysis of three factors: reliability, resale value and safety. It is calculated based on the latest research and analysis by our data science team. The data analysis comes from over 12 million new and used vehicles in our Longest-Lasting Cars and 5-Year Depreciation Studies, combined with NHTSA and IIHS Safety Ratings.
Vehicles are scored in three categories:
Reliability
The reliability score represents an analysis of iSeeCars' proprietary research on the longest-lasting vehicles.
Value Retention
The value retention score is based on our data science team's statistical analysis and prediction of 5-year depreciation from MSRP to determine which cars hold their value best, using US Bureau of Labor Statistics data to adjust for inflation.
Safety
The safety score is calculated based on the last five years of crash test ratings from the National Highway Traffic Safety Administration (NHTSA) and incorporates the latest Top Safety Pick information from the Insurance Institute for Highway Safety (IIHS).