
Best Family Luxury Midsize Cars for 2026
These are the best family luxury midsize cars ranked by iSeeCars' analysis of each vehicle’s reliability and NHTSA and IIHS safety ratings, along with key family-friendly features.
The best family luxury midsize car is the Mercedes-Benz E-Class with an iSeeCars’ Family Car Score of 8.4 out of 10. Family Car Score factors in both the reliability (based on iSeeCars’ proprietary analysis of a vehicle’s longevity) and safety (based on NHTSA and IIHS ratings) of each vehicle. In addition, iSeeCars considers the family friendly features each vehicle has across safety, storage and towing, comfort, and connectivity to rank the best family vehicles. The second best family luxury midsize car is the Lexus ES 350 with a Family Car Score of 7.7. Ranked third is the Lexus ES 250 with a rating of 7.7.
The best family luxury midsize car is the Mercedes-Benz E-Class with an iSeeCars’ Family Car Score of 8.4 out of 10. Family Car Score factors in both the reliability (based on iSeeCars’ proprietary analysis of a vehicle’s longevity) and safety (based on NHTSA and IIHS ratings) of each vehicle. In addition, iSeeCars considers the family friendly features each vehicle has across safety, storage and towing, comfort, and connectivity to rank the best family vehicles. The second best family luxury midsize car is the Lexus ES 350 with a Family Car Score of 7.7. Ranked third is the Lexus ES 250 with a rating of 7.7.
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Family Car Score 8.4 / 10
- Starting MSRP: 63900
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.8 / 10
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Value Retention 7.3 / 10
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Safety 9.0 / 10
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Family Car Score 7.7 / 10
- Starting MSRP: 42140
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.4 / 10
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Value Retention 8.3 / 10
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Safety 8.0 / 10
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Family Car Score 7.7 / 10
- Starting MSRP: 42140
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.4 / 10
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Value Retention 8.2 / 10
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Safety 8.0 / 10
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.3 / 10
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Value Retention 7.8 / 10
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Safety 8.0 / 10
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.0 / 10
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Value Retention 7.1 / 10
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Safety 8.0 / 10
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Family Car Score Not Available
- Starting MSRP: 58300
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.3 / 10
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Safety Not Available
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Family Car Score Not Available
- Starting MSRP: 60500
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.8 / 10
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Value Retention 7.1 / 10
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Safety 7.0 / 10
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Family Car Score Not Available
- Starting MSRP: 58450
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.5 / 10
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Safety 10 / 10
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Family Car Score Not Available
- Starting MSRP: 75900
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.3 / 10
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Safety Not Available
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Family Car Score Not Available
- Starting MSRP: 85700
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.2 / 10
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Safety Not Available
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Family Car Score Not Available
- Starting MSRP: 58300
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 8.0 / 10
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Safety 8.0 / 10
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Family Car Score Not Available
- Starting MSRP: 49200
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.9 / 10
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Safety 8.0 / 10
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Family Car Score Not Available
- Starting MSRP: 140000
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.2 / 10
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Safety Not Available
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Family Car Score Not Available
- Starting MSRP: 94500
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.1 / 10
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Safety Not Available
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Family Car Score Not Available
- Starting MSRP: 94500
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 7.6 / 10
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Safety Not Available
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Family Car Score Not Available
- Starting MSRP: 101050
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
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Value Retention 8.4 / 10
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Safety Not Available
Mercedes-Benz E-Class (coupe)
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Family Car Score Not Available
- Starting MSRP: 69750
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.8 / 10
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Value Retention 7.7 / 10
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Safety Not Available
Maserati Ghibli
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Family Car Score Not Available
- Starting MSRP: 109500
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.9 / 10
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Value Retention 7.1 / 10
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Safety Not Available
Jaguar XF
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Family Car Score Not Available
- Starting MSRP: 49800
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.8 / 10
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Value Retention 7.2 / 10
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Safety Not Available
BMW M5
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Family Car Score Not Available
- Starting MSRP: 109900
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.7 / 10
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Value Retention 7.3 / 10
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Safety Not Available
Related Rankings
How We Rank These Cars
The Best Family Cars rank vehicles by iSeeCars' analysis of each vehicle’s reliability and NHTSA and IIHS safety ratings, along with key family-friendly features.
The best family vehicle is specific to one or more trim levels for a given vehicle model, and has the highest combined reliability and safety score as well as the most important family-friendly features. In the event there is a tie, we use iSeeCars proprietary rating of the overall quality of the car (iSeeCars Score) to break the tie.
Separately, the overall iSeeCars Score shown for each vehicle is an analysis of three factors: reliability, resale value and safety. It is calculated based on the latest research and analysis by our data science team. The data analysis comes from over 12 million new and used vehicles in our Longest-Lasting Cars and 5-Year Depreciation Studies, combined with NHTSA and IIHS Safety Ratings.
Vehicles are scored in three categories:
Reliability
The reliability score represents an analysis of iSeeCars' proprietary research on the longest-lasting vehicles.
Value Retention
The value retention score is based on our data science team's statistical analysis and prediction of 5-year depreciation from MSRP to determine which cars hold their value best, using US Bureau of Labor Statistics data to adjust for inflation.
Safety
The safety score is calculated based on the last five years of crash test ratings from the National Highway Traffic Safety Administration (NHTSA) and incorporates the latest Top Safety Pick information from the Insurance Institute for Highway Safety (IIHS).



















