
Best Used Luxury Midsize Cars Under $40k for 2026
The best used luxury midsize cars under $40k based on a data-driven analysis of each vehicle's reliability, resale value and safety.
The best used luxury midsize car under $40k is the 2022 Mercedes-Benz E-Class based on our analysis of 12 million vehicles to assess their reliability, resale value and safety. The 2022 Mercedes-Benz E-Class has an average price of $39,692 with an overall iSeeCars score of 8. Behind the E-Class is the 2023 Lexus ES 350 with average used car price of $38,243 and iSeeCars score of 7.9. The number 3 best used luxury midsize car under $40k is the 2024 Lexus ES 250 at $38,948 average price and 7.9 iSeeCars rating. For this analysis, iSeeCars looked at used luxury midsize cars under $40k that are 1 to 6 years old to determine the latest model year vehicles that are within the price range of $35,000 to $40,000.
The best used luxury midsize car under $40k is the 2022 Mercedes-Benz E-Class based on our analysis of 12 million vehicles to assess their reliability, resale value and safety. The 2022 Mercedes-Benz E-Class has an average price of $39,692 with an overall iSeeCars score of 8. Behind the E-Class is the 2023 Lexus ES 350 with average used car price of $38,243 and iSeeCars score of 7.9. The number 3 best used luxury midsize car under $40k is the 2024 Lexus ES 250 at $38,948 average price and 7.9 iSeeCars rating. For this analysis, iSeeCars looked at used luxury midsize cars under $40k that are 1 to 6 years old to determine the latest model year vehicles that are within the price range of $35,000 to $40,000.
-
iSeeCars Score: 8.0 / 10
- Average Used Car Price: 39692.304089
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.8 / 10
-
Value Retention 7.3 / 10
-
Safety 9.0 / 10
-
iSeeCars Score: 7.9 / 10
- Average Used Car Price: 38243.142045
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.4 / 10
-
Value Retention 8.3 / 10
-
Safety 8.0 / 10
-
iSeeCars Score: 7.9 / 10
- Average Used Car Price: 38947.710938
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.4 / 10
-
Value Retention 8.2 / 10
-
Safety 8.0 / 10
-
iSeeCars Score: 7.7 / 10
- Average Used Car Price: 37009.370729
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.3 / 10
-
Value Retention 7.8 / 10
-
Safety 8.0 / 10
-
iSeeCars Score: 7.4 / 10
- Average Used Car Price: 38897.780669
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 7.0 / 10
-
Value Retention 7.1 / 10
-
Safety 8.0 / 10
6. 2021 Maserati Ghibli
-
iSeeCars Score: 7.0 / 10
- Average Used Car Price: 35648.036036
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.9 / 10
-
Value Retention 7.1 / 10
-
Safety Not Available
7. 2023 Jaguar XF
-
iSeeCars Score: 7.0 / 10
- Average Used Car Price: 36312.764706
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.8 / 10
-
Value Retention 7.2 / 10
-
Safety Not Available
-
iSeeCars Score: 7.0 / 10
- Average Used Car Price: 37416.285034
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability 6.8 / 10
-
Value Retention 7.1 / 10
-
Safety 7.0 / 10
-
iSeeCars Score: Not Available
- Average Used Car Price: 37342.384615
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
-
Value Retention 8.0 / 10
-
Safety 8.0 / 10
-
iSeeCars Score: Not Available
- Average Used Car Price: 38223.517391
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
-
Value Retention 7.9 / 10
-
Safety 8.0 / 10
-
iSeeCars Score: Not Available
- Average Used Car Price: 35352.582133
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
-
Value Retention 7.5 / 10
-
Safety 10 / 10
-
iSeeCars Score: Not Available
- Average Used Car Price: 37365.0
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
-
Value Retention 7.3 / 10
-
Safety Not Available
-
iSeeCars Score: Not Available
- Average Used Car Price: 38650.647059
iSeeCars Best Car Rankings are calculated based on an analysis of data from over 12 million cars that assesses how long each vehicle lasts and how well it retains its value over time, along with safety data from the National Highway Traffic Safety Association
See how we rank these cars-
Reliability Coming soon
-
Value Retention 7.3 / 10
-
Safety Not Available
Related Rankings
How We Rank These Cars
iSeeCars Best Used Cars Under $40k Rankings are calculated based on the latest research by our data science team and the National Highway Traffic Safety Administration (NHTSA).
We analyze data from over 12 million new and used vehicles in our Longest-Lasting Cars and 5-Year Depreciation Studies, combined with the NHTSA's Safety Ratings to give you an unbiased guide to the best vehicles in each segment.
After being evaluated, vehicles with the highest average scores earn a spot in the iSeeCars Best Car Rankings. (No final score is given to vehicles missing a score in any of the categories, but scores for other categories are still shown.)
Vehicles are scored in three categories:
Reliability
The reliability score represents an analysis of iSeeCars' proprietary research on the longest-lasting vehicles.
Value Retention
The value retention score is based on our data science team's statistical analysis and prediction of 5-year depreciation from MSRP to determine which cars hold their value best, using US Bureau of Labor Statistics data to adjust for inflation.
Safety
The safety score is calculated based on the last five years of crash test ratings from the National Highway Traffic Safety Administration (NHTSA) and incorporates the latest Top Safety Pick information from the Insurance Institute for Highway Safety (IIHS).












